Evidence map›Paper›PMID 37745567›Full record

ArticlebioRxiv : the preprint server for biology2023

Dendrite intercalation between epidermal cells tunes nociceptor sensitivity to mechanical stimuli in

Kory P Luedke, Jiro Yoshino, Chang Yin, Nan Jiang, Jessica M Huang, Kevin Huynh, Jay Z Parrish

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kory P LuedkeDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Jiro YoshinoDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Chang YinDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Nan JiangDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Jessica M HuangDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Kevin HuynhDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Jay Z ParrishDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
University of Washington · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NEUROBIOLOGYT32GM007108 · NIGMS · UNIVERSITY OF WASHINGTON · PI BINDER, MARC D · 1985 to 2014
$6.1M
Structural and functional coupling of epidermis to somatosensory neurons in DrosophilaR01NS076614 · NINDS · UNIVERSITY OF WASHINGTON · PI BAUTISTA, DIANA MICHELE, PARRISH, JAY Z · 2011 to 2023
$4.2M
Identification of proteins that structurally couple epidermal cells to somatosensory neuronsR21NS125795 · NINDS · UNIVERSITY OF WASHINGTON · PI PARRISH, JAY Z, ROGERS, STEPHEN · 2021 to 2021
$442k
NIGMS NIH HHS T32 GM007108NIH HHS P40 OD018537NINDS NIH HHS R01 NS076614NINDS NIH HHS R21 NS125795
6 · The paper itself

Abstract

An animal's skin provides a first point of contact with the sensory environment, including noxious cues that elicit protective behavioral responses. Nociceptive somatosensory neurons densely innervate and intimately interact with epidermal cells to receive these cues, however the mechanisms by which epidermal interactions shape processing of noxious inputs is still poorly understood. Here, we identify a role for dendrite intercalation between epidermal cells in tuning sensitivity of

Identifiers

PMID37745567
PMCPMC10515945
OpenAlexW4386768054

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.