Evidence map›Paper›PMID 37745547›Full record

ArticlebioRxiv : the preprint server for biology2023

GABA Release From Central Amygdala Neurotensin Neurons Differentially Modulates Reward and Consummatory Behavior in Male and Female Mice.

Graydon B Gereau, María L Torruella-Suárez, Sarah E Sizer, Mengfan Xia, Diana Zhou, Luke A Wykoff, Adonay T Teklezghi, Ali Alvarez-Pamir, Kristen M Boyt, Thomas L Kash and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Graydon B GereauBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.ORCID 0000-0003-2928-5743
María L Torruella-SuárezBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Sarah E SizerBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.ORCID 0000-0003-0210-6215
Mengfan XiaBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Diana ZhouBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Luke A WykoffBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Adonay T TeklezghiBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.ORCID 0000-0003-3363-8062
Ali Alvarez-PamirBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Kristen M BoytBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.
Thomas L KashBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.ORCID 0000-0002-4747-4495
Zoé A McElligottBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, USA.ORCID 0000-0002-4717-5698
University of North Carolina at Chapel Hill · US

Funding

Probing Ethanol Induced Acceleration of Hindbrain and Amygdalar Pathology in an Alzheimer’s Disease ModelU01AA020911 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas L. Kash, Zoe Anastasia McElligott · 2012 to 2026
$5.8M
Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behaviorR01NS122230 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KASH, THOMAS L. · 2021 to 2025
$2.0M
Probing central amygdala neurotensin neurons in alcohol consumptionR01AA026363 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCELLIGOTT, ZOE ANASTASIA · 2020 to 2024
$2.0M
A novel platform for quantification of acute neuronal transcriptional responsesR43DA057749 · NIDA · EPICYPHER, INC. · PI SUN, ZU-WEN · 2022 to 2022
$327k
NIAAA NIH HHS R01 AA026363NIAAA NIH HHS U01 AA020911NIDA NIH HHS R43 DA057749NINDS NIH HHS R01 NS122230
6 · The paper itself

Abstract

The central nucleus of the amygdala is known to play key roles in alcohol use and affect. Neurotensin neurons in the central nucleus of the amygdala have been shown to regulate alcohol drinking in male mice. However, little is known about which neurotransmitters released by these cells drive alcohol consumption or whether these cells drive alcohol consumption in female mice. Here we show that knockdown of GABA release from central amygdala neurotensin neurons using a

Identifiers

PMID37745547
PMCPMC10515895
OpenAlexW4386754319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.