Evidence map›Paper›PMID 37745488›Full record

ArticlebioRxiv : the preprint server for biology2023

A

John Kane, Xue Li, Sudhir Kumar, Katrina A Button-Simons, Katelyn M Vendrely Brenneman, Haley Dahlhoff, Mackenzie A C Sievert, Lisa A Checkley, Douglas A Shoue, Puspendra P Singh and 14 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    A2024
5 · Who and what money

Authors and funding

24 authors at 6 institutions in 4 countries.

John KaneEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Xue LiDisease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Sudhir KumarCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Katrina A Button-SimonsEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Katelyn M Vendrely BrennemanEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Haley DahlhoffEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Mackenzie A C SievertEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Lisa A CheckleyEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Douglas A ShoueEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Puspendra P SinghEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Biley A AbatiyowCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Meseret T HaileCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Shalini NairDisease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Ann ReyesDisease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Rupam TripuraMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Tom PetoMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Dysoley LekNational Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
Stefan H I KappeCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Mehul DhordaMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Standwell C NkhomaBEI Resources, American Type Culture Collection (ATCC), Manassas, VA, USA.
Ian H CheesemanHost Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Ashley M VaughanCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Timothy J C AndersonDisease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, TX, USA.
Michael T FerdigEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
University of Notre Dame · USInfectious Disease Research Institute · USTexas Biomedical Research Institute · USMahidol University · THAmerican Type Culture Collection · USCambodia National Malaria Center · KH

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Systems genetics of artemisinin resistanceP01AI127338 · NIAID · UNIVERSITY OF NOTRE DAME · PI Michael T Ferdig, Ashley M Vaughan · 2017 to 2026
$21.3M
Mapping Drug Resistance Genes in Plasmodium falciparumR37AI048071 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI ANDERSON, TIM J · 2012 to 2021
$7.9M
MOLECULAR AND BIOCHEMICAL GENETICS LABORATORY RENOVATIONC06RR013556 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 1998 to 1998
–
NCRR NIH HHS C06 RR013556NIAID NIH HHS P01 AI127338NIAID NIH HHS R37 AI048071NIH HHS P51 OD011133Wellcome Trust
6 · The paper itself

Abstract

Piperaquine (PPQ) is widely used in combination with dihydroartemisinin (DHA) as a first-line treatment against malaria parasites. Multiple genetic drivers of PPQ resistance have been reported, including mutations in the

Identifiers

PMID37745488
PMCPMC10515748
OpenAlexW4379911184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.