Evidence map›Paper›PMID 37745472›Full record

ArticlebioRxiv : the preprint server for biology2023

The TcdE holin drives toxin secretion and virulence in

N V DiBenedetto, M Oberkampf, L Cersosimo, V Yeliseyev, L Bry, J Peltier, B Dupuy

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    2025
5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

N V DiBenedettoMassachusetts Host-Microbiome Center, Dept. Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
M OberkampfInstitut Pasteur, Université Paris-Cité, UMR-CNRS 6047, Laboratoire Pathogenèse des Bactéries Anaérobies, F-75015 Paris, France.
L CersosimoMassachusetts Host-Microbiome Center, Dept. Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
V YeliseyevMassachusetts Host-Microbiome Center, Dept. Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
L BryMassachusetts Host-Microbiome Center, Dept. Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
J PeltierInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
B DupuyInstitut Pasteur, Université Paris-Cité, UMR-CNRS 6047, Laboratoire Pathogenèse des Bactéries Anaérobies, F-75015 Paris, France.
Brigham and Women's Hospital · USCentre National de la Recherche Scientifique · FR

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
MOLECULAR ANALYSIS OF MICROBIAL PATHOGENST32AI007422 · NIAID · TUFTS UNIVERSITY BOSTON · PI Ralph R. Isberg · 1992 to 2026
$5.7M
Commensal control of C. difficile virulenceR01AI153605 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BRY, LYNN · 2021 to 2025
$3.4M
NMR-resolved dynamics of C. difficile metabolismR03AI174158 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BRY, LYNN · 2023 to 2024
$179k
NIAID NIH HHS R01 AI153605NIAID NIH HHS R03 AI174158NIAID NIH HHS T32 AI007422NIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37745472
PMCPMC10516005
OpenAlexW4386815632

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.