Evidence map›Paper›PMID 37745051›Full record

ReviewFrontiers in pharmacology2023

Drug repurposing for Alzheimer's disease from 2012-2022-a 10-year literature review.

Monika E Grabowska, Annabelle Huang, Zhexing Wen, Bingshan Li, Wei-Qi Wei

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monika E GrabowskaDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Annabelle HuangDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Zhexing WenDepartments of Psychiatry and Behavioral Sciences, Cell Biology, and Neurology, Emory University School of Medicine, Atlanta, GA, United States.
Bingshan LiDepartment of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, United States.
Wei-Qi WeiDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
Drug repositioning for Alzheimer's disease via genetics, electronic health records, and human iPSC modelsR01AG069900 · NIA · VANDERBILT UNIVERSITY · PI LI, BINGSHAN, WEI, WEI-QI · 2021 to 2025
$4.0M
Towards a better understanding of genetic architecture of Alzheimer's disease with human iPSC modelsR01AG065611 · NIA · EMORY UNIVERSITY · PI LI, BINGSHAN, WEN, ZHEXING · 2020 to 2024
$3.8M
PheMAP: Measured, Automated Profile to Facilitate High Throughput PhenotypingR01GM139891 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEI, WEI-QI · 2021 to 2024
$1.7M
Computational drug repurposing for Alzheimer's diseaseF30AG080885 · NIA · VANDERBILT UNIVERSITY · PI Monika Eliana Grabowska · 2023 to 2026
$177k
NIA NIH HHS F30 AG080885NIA NIH HHS R01 AG065611NIA NIH HHS R01 AG069900NIGMS NIH HHS R01 GM139891NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseasedrug repurposingelectronic health recordsreal-world datavalidation

Identifiers

PMID37745051
PMCPMC10512468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.