ArticleExposome2023
The ethical aspects of exposome research: a systematic review.
Article in Exposome, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- From genes to environment: A life-course approach to prevent pediatric autoimmune diseases.World journal of clinical pediatrics · 2026Review
- The Digital Exposome: A Life Course Framework for Health in the Digital Age.Journal of medical Internet research · 2026Article
- Genomic Impacts of Biological Exposures.Journal of developmental biology · 2026Review
- Charting exposomethics: a roadmap for the ethical foundations of the human exposome project.Human genomics · 2026Review
- The Exposome journal on hiatus: not even a flesh wound.Exposome · 2026Article
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- A Qualitative Study of the Ethics of Community Scientists' Role in Environmental Health Research from the Perspective of Community Scientists and Institutional Review Board Staff.Environmental health perspectives · 2025Article
- Integrating exposomics into biomedicine.Science (New York, N.Y.) · 2025Article
- Exposomics: a review of methodologies, applications, and future directions in molecular medicine.EMBO molecular medicine · 2025Review
- Global research trends on the human exposome: a bibliometric analysis (2005-2024).Environmental science and pollution research international · 2025Review
- Reconceptualizing and Defining Exposomics within Environmental Health: Expanding the Scope of Health Research.Environmental health perspectives · 2024Article
- Application of Pan-Omics Technologies in Research on Important Economic Traits for Ruminants.International journal of molecular sciences · 2024Review
- Integrating longitudinal mental health data into a staging database: harnessing DDI-lifecycle and OMOP vocabularies within the INSPIRE Network Datahub.Frontiers in big data · 2024Article
- Integrating the exposome and one health approach to national health surveillance: an opportunity for Latin American countries in health preventive management.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, exposome research has been put forward as the next frontier for the study of human health and disease. Exposome research entails the analysis of the totality of environmental exposures and their corresponding biological responses within the human body. Increasingly, this is operationalized by big-data approaches to map the effects of internal as well as external exposures using smart sensors and multiomics technologies. However, the ethical implications of exposome research are still only rarely discussed in the literature. Therefore, we conducted a systematic review of the academic literature regarding both the exposome and underlying research fields and approaches, to map the ethical aspects that are relevant to exposome research. We identify five ethical themes that are prominent in ethics discussions: the goals of exposome research, its standards, its tools, how it relates to study participants, and the consequences of its products. Furthermore, we provide a number of general principles for how future ethics research can best make use of our comprehensive overview of the ethical aspects of exposome research. Lastly, we highlight three aspects of exposome research that are most in need of ethical reflection: the actionability of its findings, the epidemiological or clinical norms applicable to exposome research, and the meaning and action-implications of bias.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.