Evidence map›Paper›PMID 37744926›Full record

ArticleFrontiers in microbiology2023

Investigation of the individual genetic evolution of SARS-CoV-2 in a small cluster during the rapid spread of the BF.5 lineage in Tokyo, Japan.

Bo Jin, Rieko Oyama, Yoko Tabe, Koji Tsuchiya, Tetsuya Hando, Mitsuru Wakita, Yan Yan, Mizue Saita, Satomi Takei, Yuki Horiuchi and 4 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bo JinDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, China.
Rieko OyamaDepartment of Research Support Utilizing Bioresource Bank, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yoko TabeDepartment of Research Support Utilizing Bioresource Bank, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Koji TsuchiyaDepartment of Clinical Laboratory, Juntendo University Hospital, Tokyo, Japan.
Tetsuya HandoDepartment of Clinical Laboratory, Juntendo University Hospital, Tokyo, Japan.
Mitsuru WakitaDepartment of Clinical Laboratory, Juntendo University Hospital, Tokyo, Japan.
Yan YanDepartment of General Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Mizue SaitaDepartment of General Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Satomi TakeiDepartment of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yuki HoriuchiDepartment of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Takashi MiidaDepartment of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Toshio NaitoDepartment of Research Support Utilizing Bioresource Bank, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazuhisa TakahashiDepartment of Research Support Utilizing Bioresource Bank, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hideoki OgawaDepartment of Dermatology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been a decreasing trend in new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases and fatalities worldwide. The virus has been evolving, indicating the potential emergence of new variants and uncertainties. These challenges necessitate continued efforts in disease control and mitigation strategies. We investigated a small cluster of SARS-CoV-2 Omicron variant infections containing a common set of genomic mutations, which provided a valuable model for investigating the transmission mechanism of genetic alterations. We conducted a study at a medical center in Japan during the Omicron surge (sub-lineage BA.5), sequencing the entire SARS-CoV-2 genomes from infected individuals and evaluating the phylogenetic tree and haplotype network among the variants. We compared the mutations present in each strain within the BA.5 strain, TKYnat2317, which was first identified in Tokyo, Japan. From June 29

Indexed as

BF.5 lineageclustergene mutationintra-host evolutionomicron variantSARS-CoV-2whole genome sequencingwithin-host diversity

Identifiers

PMID37744926
PMCPMC10516552

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.