Evidence map›Paper›PMID 37744681›Full record

ArticleInfection prevention in practice2023

Contamination dynamics of personal protective equipment (PPE) by SARS-CoV-2 RNA in a makeshift hospital with COVID-19 positive occupants.

Tingting Xia, Shi Shi, Jinyan Yang, Dan Sun, Jijiang Suo, Huihui Kuang, Nana Sun, Hongyan Hu, Jinhan Xiao, Zhongqiang Yan

Abstract read
In one paragraph

Article in Infection prevention in practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tingting XiaDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Shi ShiDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Jinyan YangDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Dan SunDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Jijiang SuoDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Huihui KuangDepartment of Laboratory Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Nana SunDepartment of Laboratory Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Hongyan HuDepartment of Laboratory Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Jinhan XiaoDepartment of Rehabilitation Physiotherapy, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.
Zhongqiang YanDepartment of Disease Prevention and Control, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Personal protective equipment (PPE) helps protect healthcare workers (HCWs) from infection and prevents cross-contamination. Knowledge of the contamination dynamics of PPE during the management of COVID-19 patients in a makeshift hospital is limited. Aim: To describe the rate of SARS-CoV-2 contamination in PPE and to assess the change of contamination at different time points. Methods: HCWs were followed up for up to 4 hours with hourly collection of swab samples from PPE surfaces in a makeshift COVID-19 hospital setting. Swabs were tested using quantitative reverse transcription polymerase chain reaction (RT-qPCR) for SARS-CoV-2 RNA. Results: SARS-CoV-2 was detected on 50.9% of the 1620 swabbed samples from 9 different sites of full-body PPE worn by HCWs. The proportion of sites contaminated with SARS-CoV-2 RNA varied from 10.6% to 95.6%. Viral RNA was most frequently detected from the sole of the outer foot cover (95.6%) and least frequently on the face shield (10.6%). The median Ct values among positive samples were 34.20 (IQR, 32.61-35.22) and 34.05 (IQR, 32.20-35.39) for ORF1ab and N genes, respectively. The highest rate of contamination with SARS-CoV-2 RNA for the PPE swab samples was found after 3 hours of use. The positive rate of outer surface of HEPA filters from air supply device was 82.1% during the full capacity period of the makeshift hospital. Conclusion: A higher rate of contamination was identified at 3 hours after the entrance to the COVID-19 patient care area. Virus-containing aerosols were trapped in the HEPA filter of air supply equipment, representing a potential protective factor against infection to HCWs.

Indexed as

Contamination dynamicsMakeshift hospitalPersonal protective equipmentSARS-CoV-2

Identifiers

PMID37744681
PMCPMC10514403

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.