Evidence map›Paper›PMID 37744296›Full record

SynthesisWorld journal of gastroenterology2023

Regenerating gene 4 promotes chemoresistance of colorectal cancer by affecting lipid droplet synthesis and assembly.

Cong-Yu Zhang, Rui Zhang, Li Zhang, Zi-Mo Wang, Hong-Zhi Sun, Zheng-Guo Cui, Hua-Chuan Zheng

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cong-Yu ZhangCancer Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China.
Rui ZhangDepartment of Colorectal Surgery, Liaoning Cancer Hospital, Shenyang 110042, Liaoning Province, China.
Li ZhangDepartment of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China.
Zi-Mo WangCancer Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China.
Hong-Zhi SunCancer Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China.
Zheng-Guo CuiDepartment of Environmental Health, University of Fukui School of Medical Sciences, Fukui 910-1193, Japan.
Hua-Chuan ZhengCancer Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121001, Liaoning Province, China. zheng_huachuan@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegenerating gene 4

aimTo explore the role of

methodsWe conducted a meta-analysis and bioinformatics and pathological analyses of

resultsCompared to normal mucosa,

conclusion

Indexed as

Colorectal NeoplasmsDrug Resistance, NeoplasmLipid DropletsPancreatitis-Associated ProteinsDNAEpigenesis, GeneticHistonesHumansPhosphatidylinositol 3-KinasesDNAHistonesPancreatitis-Associated ProteinsPhosphatidylinositol 3-KinasesREG4 protein, humanAggressive behaviorChemoresistanceColorectal cancerEpidermal growth factor receptor signalLipid droplet formationPrognosisRegenerating gene 4

Identifiers

PMID37744296
PMCPMC10514755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.