Evidence map›Paper›PMID 37744276›Full record

ReviewOncology research2023

Progress in research on tumor microenvironment-based spatial omics technologies.

Fangmei Xie, Naite Xi, Zeping Han, Wenfeng Luo, Jian Shen, Jinggeng Luo, Xingkui Tang, Ting Pang, Yubing Lv, Jiabing Liang and 5 more

Abstract readReview
In one paragraph

Review in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fangmei XieCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Naite XiCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Zeping HanCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Wenfeng LuoCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Jian ShenCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Jinggeng LuoDepartment of General Surgery, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Xingkui TangDepartment of General Surgery, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Ting PangCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Yubing LvCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Jiabing LiangCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Liyin LiaoCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Haoyu ZhangCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Yong JiangCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.
Yuguang LiAdministrating Office, He Xian Memorial Hospital, Southern Medical University, Guangzhou, China.
Jinhua HeCentral Laboratory, Panyu Central Hospital of Guangzhou, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatial omics technology integrates the concept of space into omics research and retains the spatial information of tissues or organs while obtaining molecular information. It is characterized by the ability to visualize changes in molecular information and yields intuitive and vivid visual results. Spatial omics technologies include spatial transcriptomics, spatial proteomics, spatial metabolomics, and other technologies, the most widely used of which are spatial transcriptomics and spatial proteomics. The tumor microenvironment refers to the surrounding microenvironment in which tumor cells exist, including the surrounding blood vessels, immune cells, fibroblasts, bone marrow-derived inflammatory cells, various signaling molecules, and extracellular matrix. A key issue in modern tumor biology is the application of spatial omics to the study of the tumor microenvironment, which can reveal problems that conventional research techniques cannot, potentially leading to the development of novel therapeutic agents for cancer. This paper summarizes the progress of research on spatial transcriptomics and spatial proteomics technologies for characterizing the tumor immune microenvironment.

Indexed as

FibroblastsTumor MicroenvironmentGene Expression ProfilingHumansTechnologySpatial omicsSpatial proteomicsSpatial transcriptomicsTumor microenvironment

Identifiers

PMID37744276
PMCPMC10513957

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.