Evidence map›Paper›PMID 37744191›Full record

ArticleArchives of rehabilitation research and clinical translation2023

The Critical Period After Stroke Study (CPASS) Upper Extremity Treatment Protocol.

Jessica Barth, Shashwati Geed, Abigail Mitchell, Kathaleen P Brady, Margot L Giannetti, Alexander W Dromerick, Dorothy F Edwards

Registry-linked trialAbstract read
In one paragraph

Article in Archives of rehabilitation research and clinical translation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07661849 (Efficacy of Tele-CPASS, a Telerehabilitation Intervention Using Critical Periods After Stroke Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07661849 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Tele-CPASS, a Telerehabilitation Intervention Using Critical Periods After Stroke Study (CPASS) Compared to In-person CPASS for Upper Extremity Motor Recovery

TypeinterventionalSponsorUniversity of Texas, El PasoRan2025 to 2029Enrolled42ConditionsStroke, Hemiparesis, Upper Extremity Impairments, Stroke RehabilitationArmsTele-CPASS, In-person CPASS therapy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessica BarthVeterans Affairs Medical Center, Center of Innovation for Long-Term Supports and Services, Providence, RI.
Shashwati GeedMedStar National Rehabilitation Hospital, Washington, DC.
Abigail MitchellMedStar National Rehabilitation Hospital, Washington, DC.
Kathaleen P BradyMedStar National Rehabilitation Hospital, Washington, DC.
Margot L GiannettiMedStar National Rehabilitation Hospital, Washington, DC.
Alexander W DromerickMedStar National Rehabilitation Hospital, Washington, DC.
Dorothy F EdwardsUniversity of Wisconsin-Madison School of Medicine and Public Health, Madison, WI.

Funding

Neurorehabilitation and Restorative Neuroscience NetworkK12HD093427 · NICHD · GEORGETOWN UNIVERSITY · PI BREGMAN, BARBARA S, DROMERICK, ALEXANDER W · 2017 to 2021
$3.9M
Stroke Central Atlantic Network for Research (SCANR)U24NS107222 · NINDS · MEDSTAR HEALTH RESEARCH INSTITUTE · PI Amie Hsia, Peter Ethan Turkeltaub · 2018 to 2026
$2.6M
NICHD NIH HHS K12 HD093427NINDS NIH HHS U24 NS107222
6 · The paper itself

Abstract

Objective: To present the development of a novel upper extremity (UE) treatment and assess how it was delivered in the Critical Periods After Stroke Study (CPASS), a phase II randomized controlled trial (RCT). Design: Secondary analysis of data from the RCT. Setting: Inpatient and outpatient settings the first year after stroke. Participants: Of the 72 participants enrolled in CPASS (N=72), 53 were in the study groups eligible to receive the treatment initiated at ≤30 days (acute), 2-3 months (subacute), or ≥6 months (chronic) poststroke. Individuals were 65.1±10.5 years of age, 55% were women, and had mild to moderate UE motor capacity (Action Research Arm Test=17.2±14.3) at baseline. Intervention: The additional 20 hours of treatment began using the Activity Card Sort (ACS), a standardized assessment of activities and participation after stroke, to identify UE treatment goals selected by the participants that were meaningful to them. Treatment activities were broken down into smaller components from a standardized protocol and process that operationalized the treatments essential elements. Main Outcome Measures: Feasibility of performing the treatment in a variety of clinical settings in an RCT and contextual factors that influenced adherence. Results: A total of 49/53 participants fully adhered to the CPASS treatment. The duration and location of the treatment sessions and the UE activities practiced during therapy are presented for the total sample (n=49) and per study group as an assessment of feasibility and the contextual factors that influenced adherence. Conclusions: The CPASS treatment and therapy goals were explicitly based on the meaningful activities identified by the participants using the ACS as a treatment planning tool. This approach provided flexibility to customize UE motor therapy without sacrificing standardization or quantification of the data regardless of the location and UE impairments of participants within the first year poststroke.

Indexed as

Clinical Trials as topicOccupational therapyRehabilitationStroke rehabilitationUpper extremity

Identifiers

PMID37744191
PMCPMC10517370

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.