Evidence map›Paper›PMID 37744088›Full record

ArticleFrontiers in fungal biology2021

Biosynthesis of Antibacterial Iron-Chelating Tropolones in

Jennifer Gerke, Anna M Köhler, Jan-Peer Wennrich, Verena Große, Lulu Shao, Antje K Heinrich, Helge B Bode, Wanping Chen, Frank Surup, Gerhard H Braus

Abstract read
In one paragraph

Article in Frontiers in fungal biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Lienhwalides: Unique Tropolone-Maleidride Hybrids from Hypoxylon lienhwacheense.Chembiochem : a European journal of chemical biology · 2025
    Article
  5. Fungal COP9 signalosome assembly requires connection of two trimeric intermediates for integration of intrinsic deneddylase.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jennifer GerkeDepartment of Moleuclar Microbiology and Genetics and Göttingen Center for Molecular Biosciences (GZMB), Georg-August-Universität Göttingen, Göttingen, Germany.
Anna M KöhlerDepartment of Moleuclar Microbiology and Genetics and Göttingen Center for Molecular Biosciences (GZMB), Georg-August-Universität Göttingen, Göttingen, Germany.
Jan-Peer WennrichMicrobial Drugs Department, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.
Verena GroßeDepartment of Moleuclar Microbiology and Genetics and Göttingen Center for Molecular Biosciences (GZMB), Georg-August-Universität Göttingen, Göttingen, Germany.
Lulu ShaoMicrobial Drugs Department, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.
Antje K HeinrichMolecular Biotechnology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Helge B BodeMolecular Biotechnology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Wanping ChenDepartment of Moleuclar Microbiology and Genetics and Göttingen Center for Molecular Biosciences (GZMB), Georg-August-Universität Göttingen, Göttingen, Germany.
Frank SurupMicrobial Drugs Department, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.
Gerhard H BrausDepartment of Moleuclar Microbiology and Genetics and Göttingen Center for Molecular Biosciences (GZMB), Georg-August-Universität Göttingen, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The soil microbiome comprises numerous filamentous fungi and bacteria that mutually react and challenge each other by the production of bioactive secondary metabolites. Herein, we show in liquid co-cultures that the presence of filamentous Streptomycetes producing antifungal glycopeptide antibiotics induces the production of the antibacterial and iron-chelating tropolones anhydrosepedonin (

Indexed as

Aspergillus nidulansfungal-bacterial co-cultivationglycopeptide antibioticsStreptomycesstructure elucidationtropolones

Identifiers

PMID37744088
PMCPMC10512232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.