Evidence map›Paper›PMID 37744053›Full record

ArticleJournal of scleroderma and related disorders2023

Systemic sclerosis and primary biliary cholangitis: Longitudinal data to determine the outcomes.

Gemma Lepri, Paolo Airò, Oliver Distler, Kristofer Andréasson, Yolanda Braun-Moscovici, Eric Hachulla, Alexandra Balbir-Gurman, Ellen De Langhe, Simona Rednic, Francesca Ingegnoli and 24 more

Abstract read
In one paragraph

Article in Journal of scleroderma and related disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Gemma LepriDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-4141-6937
Paolo AiròRheumatology and Clinical Immunology, Spedali Civili of Brescia, Brescia, Italy.ORCID https://orcid.org/0000-0001-5241-1918
Oliver DistlerDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
Kristofer AndréassonSection of Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden.ORCID https://orcid.org/0000-0001-7021-2541
Yolanda Braun-MoscoviciRheumatology Department, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion, Haifa, Israel.ORCID https://orcid.org/0000-0001-7706-9346
Eric HachullaDepartment of Internal Medicine, Hôpital Claude Huriez, Lille, France.
Alexandra Balbir-GurmanRheumatology Department, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Ellen De LangheERN ReCONNET, Division of Rheumatology, University Hospitals Leuven, Leuven, Belgium.
Simona RednicDepartment of Rheumatology, Emergency County Teaching Hospital, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania.
Francesca IngegnoliClinical Rheumatology Unit, ASST Pini-CTO, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milano, Italy.
Edoardo RosatoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Laura GroseanuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Ruxandra IonescuCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Silvia Bellando-RandoneDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Liudmila GarzanovaLaboratory of Microcirculation and Inflammation, VA Nasonova Institute of Rheumatology, Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-5012-0540
Lorenzo BerettaScleroderma Unit, Referral Center for Systemic Autoimmune Diseases, La Fondazione IRCCS Ca' Granda Ospedale Maggiore di Milano Policlinico, Milano, Italy.
Chiara BellocchiScleroderma Unit, Referral Center for Systemic Autoimmune Diseases, La Fondazione IRCCS Ca' Granda Ospedale Maggiore di Milano Policlinico, Milano, Italy.ORCID https://orcid.org/0000-0001-8326-7904
Sergey MoiseevTareev Clinic of Internal Diseases, Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Pavel NovikovTareev Clinic of Internal Diseases, Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Iulia SzaboDepartment of Rheumatology, Emergency County Teaching Hospital, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania.
Dorota KrasowskaDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Veronica CodulloRheumatology, Policlinico San Matteo, Pavia, Italy.
Ulrich A WalkerDepartment of Rheumatology, Universitätsspital Basel, Basel, Switzerland.
Chrysoula ManolarakiDepartment of Rheumatology, Universitätsspital Basel, Basel, Switzerland.
Serena GuiducciDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Marie-Elise TruchetetRheumatology Department, Bordeaux University Hospital, Bordeaux, France.
Florenzo IannoneRheumatology Unit - DETO, School of Medicine, University of Bari, Bari, Italy.ORCID https://orcid.org/0000-0003-0474-5344
Lorenzo TofaniDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Cosimo BruniDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-2813-2083
Vanessa SmithDepartment of Rheumatology, Ghent University Hospital and Department of Internal Medicine, Ghent University, Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium.
Giovanna CuomoDepartment of Precision of Medicine, University of Campania - L. Vanvitelli, Naples, Italy.ORCID https://orcid.org/0000-0002-4292-3589
Martin KruscheDivision of Rheumatology and Systemic Inflammatory Diseases, University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.
Marco Matucci-CerinicDivision of Rheumatology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Yannick AllanoreRheumatology, Cochin Hospital, APHP, Paris Cité University, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several studies described the cross-sectional characteristics of systemic sclerosis patients and coexisting primary biliary cholangitis, but longitudinal prognostic data are lacking. Aims: To describe the systemic sclerosis-primary biliary cholangitis phenotype, including baseline characteristics and outcomes. Methods: We performed a multicentre the European Scleroderma Trials and Research Group study of systemic sclerosis patients with primary biliary cholangitis or with primary biliary cholangitis-specific antibodies, matched with systemic sclerosis controls free from hepatobiliary involvement matched for disease duration and cutaneous subset. Data were recorded at baseline and at the last available visit. Results: A total of 261 patients were enrolled (115 primary biliary cholangitis-systemic sclerosis, 161 systemic sclerosis). At baseline, systemic sclerosis-primary biliary cholangitis patients had a higher prevalence of anti-centromere antibodies ( Conclusion: Our data show that systemic sclerosis-primary biliary cholangitis exhibit a mild systemic sclerosis and primary biliary cholangitis phenotype with outcomes being in general favourable.

Indexed as

autoimmunityfibrotic diseasesoutcomesoverlap syndromeprimary biliary cholangitisSystemic sclerosis

Identifiers

PMID37744053
PMCPMC10515998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.