Evidence map›Paper›PMID 37744005›Full record

ArticleMolecular therapy. Methods & clinical development2023

Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy.

Daniel Nunez, Darshil Patel, Jenell Volkov, Steven Wong, Zachary Vorndran, Fabian Müller, Michael Aigner, Simon Völkl, Andreas Mackensen, Georg Schett and 1 more

Abstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Trial
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  6. Article
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  8. Can we cure autoimmunity?Current opinion in immunology · 2026
    Review
  9. Review
  10. Distinct autoreactive CD19Nature communications · 2025
    Article
  11. Article
  12. Lupus nephritis.Nature reviews. Disease primers · 2025
    Review
  13. Review
  14. Review
  15. Targeting human plasma cells using regulated BCMA CAR T cells eliminates circulating antibodies in humanized mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. CAR-T cell therapy embarks on autoimmune disease.Bone marrow transplantation · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel NunezDepartment of Computational Biology, Cabaletta Bio, Philadelphia, PA, USA.
Darshil PatelDepartment of Protein and Molecular Biology, Cabaletta Bio, Philadelphia, PA, USA.
Jenell VolkovDepartment of Translational Medicine, Cabaletta Bio, Philadelphia, PA, USA.
Steven WongDepartment of Protein and Molecular Biology, Cabaletta Bio, Philadelphia, PA, USA.
Zachary VorndranDepartment of Translational Medicine, Cabaletta Bio, Philadelphia, PA, USA.
Fabian MüllerDepartment of Medicine 5, Haematology and Oncology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Michael AignerDepartment of Medicine 5, Haematology and Oncology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Simon VölklDepartment of Medicine 5, Haematology and Oncology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Andreas MackensenDepartment of Medicine 5, Haematology and Oncology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Georg SchettDepartment of Medicine 3, Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany.
Samik BasuDepartment of Translational Medicine, Cabaletta Bio, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chimeric antigen receptor (CAR) T cells targeting CD19

Indexed as

antibodiesautoimmune diseaseCARchimeric antigen receptor T cellcytokinesSLEsystemic lupus erythematousvaccines

Identifiers

PMID37744005
PMCPMC10514439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.