Observational studyBMC oral health2023
Antibiotic prophylaxis and surgical site infections in orthognathic surgery - a retrospective analysis.
Observational study in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Somatic and psychiatric aspects of complications outside the surgical area in orthognathic surgery: A retrospective study of 429 patients.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Is single-shot antibiotic prophylaxis really enough for standard OMF-surgeries?Clinical oral investigations · 2026Article
- Recommendation of antibiotic prophylaxis in orthognathic surgery according to current microbial resistance, a retrospective analysis of 100 operated cases.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Rational utilization of antibiotic prophylaxis in oral and maxillofacial surgery: a large scope review of recent data.BMC oral health · 2025Review
- Retrospective Analysis of Surgical Site Infection After Titanium Plate Removal Following Orthognathic Surgery.Journal of clinical medicine · 2025Article
- PLLA Coating of Lyophilized Human Bone Allograft for Long-term Release of Antibiotics.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was conducted to determine surgical site infection (SSI) rates and potential risk factors as well as to evaluate antibiotic prophylaxis in orthognathic surgery.
methodsThis retrospective observational study included patients who received orthognathic surgery. SSIs and their management were assessed for up to one year post-operatively. The applied antibiotic regime and other possible influencing factors (smoking, age, site of infection, drainage, duration of surgery, displacement distances, craniofacial malformations) were assessed.
resultsIn total 291 patient met the inclusion criteria (56.7% female). The mean age at surgery was 25.5 ± 8.5 years. Fifty-four patients (18.6%) were diagnosed with a craniofacial malformation. Relevant previous surgeries were documented in about one quarter of included patients (n = 75). Ninety-two percent of patients (n = 267) received intraoperative single-dose antibiotic prophylaxis. Surgical site infections occurred in 12.4% (n = 36) of patients. There was a significant association between postoperative infections and type of surgery (P = .037) as well as type of drainage (P = .002). Statistical analyses also revealed a higher prevalence of smokers (P = .036) and previous surgically assisted rapid palatal expansion (SARPE) (P = .018) in the infection group. Furthermore, no significant relationships were observed between postoperative infections and various co-factors (i.e. antibiotic regime, age at surgery, gender, associated craniofacial malformations, surgery duration, displacement distances, mandibular setback vs. advancement).
conclusionLow rates of SSIs occurred following an intraoperative single-dose antibiotic regime. None of the SSIs had a significant effect on the final surgical outcome. Present data do not warrant escalation of the antibiotic regimen. Postoperative smoking and capillary drainage should be avoided.
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