ArticleJournal of gynecologic oncology2024
Predictive factors of surgical complications after pelvic exenteration for gynecological malignancies: a large single-institution experience.
Article in Journal of gynecologic oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Impact of Pre-Operative Nutritional Status on Postoperative Outcomes Following Pelvic Exenteration: A Systematic Review and Meta-Analysis.ANZ journal of surgery · 2026Pooled it
- Evaluation of survival and mortality in pelvic exenteration for gynecologic malignancies: a systematic review, meta-analyses, and meta-regression study.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2025Pooled it
- Imaging in pelvic exenteration-a multidisciplinary practice guide from the ESGAR-SAR-ESUR-PelvEx collaborative group.European radiology · 2025Guideline
- Efficacy and safety of camrelizumab for the treatment of cervical cancer: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Morbidity, Recurrence and Survival Following Pelvic Exenteration for Gynaecological Malignancies: A Retrospective, Single-Centre Study.Journal of clinical medicine · 2026Article
- Incidence of postoperative fever and bloodstream infections in gynecological surgical patients: a three-year retrospective surveillance.BMC infectious diseases · 2025Article
- Article
- Damage Control Surgery in Obstetrics and Gynecology: Abdomino-Pelvic Packing in Multimodal Hemorrhage Management.Journal of clinical medicine · 2025Review
- Review
- Perioperative Risk Prediction in Major Gynaecological Oncology Surgery: A National Diagnostic Survey of UK Clinical Practice.Diagnostics (Basel, Switzerland) · 2025Article
- Review
- Modified posterior pelvic exenteration combined with ileocecal resection for locally advanced endometrial cancer.Journal of gynecologic oncology · 2025Article
- Enhanced recovery after surgery: Narrative review in gynecologic pelvic exenterations.Frontiers in oncology · 2025Review
- Post-traumatic reactions and quality of life after pelvic exenteration for gynecologic cancer: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- New Insights into the Assessment of Peri-Operative Risk in Women Undergoing Surgery for Gynecological Neoplasms: A Call for a New Tool.Medicina (Kaunas, Lithuania) · 2024Review
- Review
- ASO Author Reflections: Quality of Life After Extended Pelvic Surgery.Annals of surgical oncology · 2024Article
Corrections and comments
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Authors and funding
20 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate pre-operative predictors of early (<30 days) severe complications (grade Dindo 3+) in patients with gynecological malignancy submitted to pelvic exenteration (PE).
methodsWe retrospectively analyzed 129 patients submitted to surgery at Fondazione Policlinico Gemelli between 2010 and 2019. We included patients affected by primary or recurrent/persistent cervical, endometrial, or vulvar/vaginal cancers. Post-operative complications were graded according to the Dindo classification. Logistic regression was used to analyze potential predictors of complications.
resultsWe performed 63 anterior PE, 10 posterior PE, and 56 total PE. The incidence of early severe post-operative complications was 27.9% (n=36), and the early mortality rate was 2.3% (n=3). More frequent complications were related to the urinary diversion and intestinal surgery. In univariable analysis, hemoglobin ≤10 g/dL (odds ratio [OR]=4.2; 95% confidence interval [CI]=1.65-10.7; p=0.003), low albumin levels (OR=3.9; 95% CI=1.27-12.11; p=0.025), diabetes (OR=4.15; 95% CI=1.22-14.1; p=0.022), 2+ comorbidities at presentation (OR=5.18; 95% CI=1.49-17.93; p=0.012) were predictors of early severe complications. In multivariable analysis, only low hemoglobin and comorbidities at presentation were independent predictors of complications.
conclusionPelvic exenteration is an aggressive surgery characterized by a high rate of post-operative complications. Pre-operative assessment of comorbidities and patient health status are crucial to better select the right candidate for this type of surgery.
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