Evidence map›Paper›PMID 37742820›Full record

ArticleComparative biochemistry and physiology. Part A, Molecular & integrative physiology2023

HoTDAM! An easy-to-use automated assay expands the inducible thermotolerance phenotype in Drosophila melanogaster: Heat hardening reduces motility.

Blase Rokusek, Sunayn Cheku, Matthew Rokusek, Christopher J Waples, Lawrence Harshman, Kimberly A Carlson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Estimating thermal death time curves inmicroPublication biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Blase RokusekDepartment of Biology, University of Nebraska at Kearney, Kearney, NE 68849, USA.
Sunayn ChekuDepartment of Biology, University of Nebraska at Kearney, Kearney, NE 68849, USA.
Matthew RokusekSchool of Computing, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Christopher J WaplesDepartment of Psychology, University of Nebraska at Kearney, Kearney, NE 68849, USA.
Lawrence HarshmanSchool of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Kimberly A CarlsonDepartment of Biology, University of Nebraska at Kearney, Kearney, NE 68849, USA. Electronic address: carlsonka1@unk.edu.
University of Nebraska at Kearney · USUniversity of Nebraska–Lincoln · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RIZZO, MATTHEW · 2016 to 2025
$42.8M
NIGMS NIH HHS P20 GM103427NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

To quantify heat tolerance in insects, two manual observation measures are typically implemented: the time to physiological collapse at a static noxious temperature (time to knockdown; TKD) or the temperature at which collapse occurs as temperature increases (critical thermal maximum; CT

Indexed as

ThermotoleranceAnimalsDrosophilaDrosophila melanogasterHot TemperaturePhenotypeActivityDrosophila activity monitorsHeat hardeningHeat toleranceLocomotionThermal limitThermal stressTime to knockdown

Identifiers

PMID37742820
PMCPMC10593110
OpenAlexW4386945929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.