Evidence map›Paper›PMID 37742192›Full record

ArticleCell reports2023

Post-synaptic GABA

Jian Zhao, Luna Gao, Stephen Nurrish, Joshua M Kaplan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Transsynaptic linking of calcium channels and postsynaptic receptors at a dyadic synapse.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. ImmatureProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. ImmaturebioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Presynaptic neurons self-tune by inversely coupling neurotransmitter release with the abundance of CaV2 voltage-gated CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jian ZhaoDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Luna GaoDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Stephen NurrishDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Joshua M KaplanDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address: kaplan@molbio.mgh.harvard.edu.
Harvard University · US

Funding

MECHANOTRANSDUCTION IN C ELEGANSR01NS032196 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JOSHUA M KAPLAN · 1993 to 2026
$8.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanotransduction in C elegansR37NS032196 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI KAPLAN, JOSHUA M · 2008 to 2014
$2.8M
NIH HHS P40 OD010440NINDS NIH HHS R01 NS032196NINDS NIH HHS R37 NS032196
6 · The paper itself

Abstract

We describe a retrograde synaptic signal at the C. elegans GABAergic neuromuscular junction. At this synapse, GABA release is controlled by two voltage-activated calcium channels (UNC-2/CaV2 and EGL-19/CaV1), and muscle responses are mediated by a single GABA receptor (UNC-49/GABA

Indexed as

Caenorhabditis elegansReceptors, GABA-AAnimalsCaenorhabditis elegans ProteinsCaveolin 2gamma-Aminobutyric AcidSynapsesSynaptic TransmissionCaenorhabditis elegans ProteinsCav-2 protein, C elegansCaveolin 2gamma-Aminobutyric AcidReceptors, GABA-ACaV2C. elegansCP: NeuroscienceGABA-Aretrograde signalsynaptic plasticityUNC-2UNC-49

Identifiers

PMID37742192
PMCPMC10873018
OpenAlexW4386985937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.