Evidence map›Paper›PMID 37741809›Full record

ReviewMolecular biology reports2023

miRNA as biomarker in lung cancer.

Esperanza Salcedo Lobera, Macarena Arroyo Varela, Rafael Larrosa Jimenez, Rocio Bautista Moreno

Abstract readReview
In one paragraph

Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. The pathophysiological role of MiRNAs in heart failure.Frontiers in cardiovascular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esperanza Salcedo LoberaU.G.C. Medico-Quirurgica de Enfermedades Respiratorias, Hospital Regional Universitario de Malaga, Malaga, Spain.
Macarena Arroyo VarelaU.G.C. Medico-Quirurgica de Enfermedades Respiratorias, Hospital Regional Universitario de Malaga, Malaga, Spain. macarroyo@gmail.com.ORCID http://orcid.org/0000-0003-4939-9174
Rafael Larrosa JimenezDepartment of Computer Architecture, University of Malaga, Malaga, Spain.
Rocio Bautista MorenoAndalusian Platform for Bioinformatics at SCBI, University of Malaga, Malaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has a high prevalence and mortality due to its late diagnosis and limited treatment, so it is essential to find biomarkers that allow a faster diagnosis and improve the survival of these patients. In this sense, biomarkers based on miRNAs have supposed a considerable advance. miRNAs, which are small RNA sequences, can regulate gene expression, so they play an essential role not only as a diagnostic biomarker but also as a therapeutic and prognostic one. Also, miRNA biomarkers can be obtained from liquid biopsies, which are less intrusive than lung biopsies, and have better accessibility, safety and repeatability, which allows using those biomarkers both for diagnosis and monitoring of patients. In this review, we highlight the importance of miRNAs and collect the existing evidence of their relationship with lung cancer.

Indexed as

Lung NeoplasmsMicroRNAsBiomarkersBiopsyHumansLiquid BiopsyBiomarkersMicroRNAsBiomarkerHigh-throughput sequencingLung cancerMicroRNARNA-seq

Identifiers

PMID37741809
PMCPMC10635960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.