Evidence map›Paper›PMID 37740918›Full record

ArticleScandinavian journal of primary health care2023

Chronic fatigue syndromes: real illnesses that people can recover from.

Oslo Chronic Fatigue Consortium, Tomas Nordheim Alme, Anna Andreasson, Tarjei Tørre Asprusten, Anne Karen Bakken, Michael Bj Beadsworth, Birgitte Boye, Per Alf Brodal, Elias Myrstad Brodwall, Kjetil Gundro Brurberg and 42 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scandinavian journal of primary health care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07407829 (Step by Step Back - A Feasibility Study of a CBT-Based Physical Activity Intervention for Stress-Related Exhaustion), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07407829 narecruitingnot on this mapstarted 2025, after this paper: background citation

Step by Step Back - A Feasibility Study of a CBT-Based Physical Activity Intervention for Stress-Related Exhaustion

TypeinterventionalSponsorThe Swedish School of Sport and Health SciencesRan2025 to 2026Enrolled20ConditionsExhaustion Disorder, Stress-Related DisordersArmsCBT/ACT-based psychologist-delivered physical activity program
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Narratives of recovery from persistent fatigue: a stepwise learning process.Scandinavian journal of primary health care · 2026
    Article
  2. Review
  3. An Overview of Severe Myalgic Encephalomyelitis.Journal of clinical medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Reply: Muscle abnormalities in Long COVID.Nature communications · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

52 authors at 19 institutions in 10 countries.

Oslo Chronic Fatigue Consortium
Tomas Nordheim AlmeDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Anna AndreassonDepartment of Clinical Epidemiology, Karolinska Institutet, Stockholm, Sweden.
Tarjei Tørre AsprustenGeneral Practitioner, Hjelmeland, Norway.
Anne Karen BakkenVID Specialized University, Oslo, Norway.
Michael Bj BeadsworthTropical and infectious Disease Unit, Royal Liverpool University Hospital. Liverpool University Hospitals Foundation Trust, Liverpool, UK.
Birgitte BoyeDepartment of Behavioral Medicine, University of Oslo, Oslo, Norway.
Per Alf BrodalInstitute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Elias Myrstad BrodwallDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Kjetil Gundro BrurbergDivision for Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Ingrid BuggeDepartment of Child and Adolescent Mental Health in Hospitals, Oslo University Hospital, Oslo, Norway.
Trudie ChalderDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
Reidar DueDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Hege Randi EriksenDepartment of Sport, Food and Natural Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Per Klausen FinkResearch Clinic for Functional Disorders and Psychosomatics. Aarhus University Hospital, Aarhus, Denmark.
Signe Agnes FlottorpCentre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.
Egil Andreas ForsFaculty of Medicine and Health Sciences, Department of Public Health and Nursing, General Practitioner Research Unit, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Bård Fossli JensenNydalen Helsehus, Oslo, Norway.
Hans Petter FundingsrudThe Child & Adolescent Health Services, University Hospital of North Norway, Tromsø, Norway.
Paul GarnerDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, England.
Lise Beier HavdalDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Helene HelgelandNational Advisory Unit on Psychosomatic Disorders in Children and Adolescents. Department of Child and Adolescent Mental Health in Hospitals, Oslo University Hospital, Oslo, Norway.
Henrik Børsting JacobsenDepartment of Pain management and research, Oslo University Hospital, Oslo, Norway.
Georg Espolin JohnsonUniversity of Oslo, Oslo, Norway.
Martin JonsjöDepartment of Behavior Medicine, Karolinskal University Hospital, Stockholm, Sweden.
Hans KnoopDepartment of Medical Psychology, Amsterdam University Medical Centres, Location University of Amsterdam, Amsterdam, The Netherlands.
Live LandmarkDepartment of Psychology, NTNU, Trondheim, Norway.
Gunvor LaunesUniversity of Bergen, Bergen, Norway.
Mats LekanderStress Research Institute, Department of psychology, Stockholm University, Division of Psychology/Osher Center for Integrative Health, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Hannah LinnrosDepartment of Health, Medicine, and Caring Sciences Pain and Rehabilitation Center, Linköping University Hospital, Linköping, Sweden.
Elin LindsäterCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Helena LiiraHelsinki University Hospital, Helsinki, Finland.
Lina LinnestadSaglia medical center, Vestby, Norway.
Jon Håvard LogeDepartment of Behavioral Medicine, University of Oslo, Oslo, Norway.
Peter Solvoll LybyCatoSenteret Rehabilitation Center, Son, Norway.
Sadaf MalikDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Ulrik Fredrik MaltDivision of Clinical Neuroscience. Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Trygve MoeChief Physician, Falck Norge, Oslo, Norway.
Anna-Karin NorlinDepartment of Health, Medicine, and Caring Sciences Pain and Rehabilitation Center, Linköping University Hospital, Linköping, Sweden.
Maria PedersenDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Siv Elin PignatielloUnit Psychosomatic medicine and CL psychiatry, Rikshospitalet, Oslo University Hospital, Oslo, Norway.
Charlotte Ulrikka RaskDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Aarhus, Denmark.
Silje Endresen RemeDepartment of Pain management and research, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-5870-4906
Gisle RoksundGeneral Practitioner, Klosterhagen Legesenter, Norway.
Markku SainioOutpatient Clinic for Functional Disorders, Helsinki University Hospital, Helsinki, Finland.
Michael SharpePsychological Medicine, University of Oxford, Oxford, UK.
Ruth Foseide ThorkildsenDepartment of Medicine, Diakonhjemmet Hospital, Oslo, Norway.
Betty van RoyDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Per Olav VandvikDepartment of Medicine, Lovisenberg Diaconal Hospital, Oslo, Norway.
Henrik VogtDepartment of Community Medicine and Global Health, Institute for Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.
Hedda Bratholm WyllerClinical Psychologist, Oslo, Norway.
Vegard Bruun Bratholm WyllerDepartment of Paediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway.
Oslo University Hospital · NOUniversity of Oslo · NOAkershus University Hospital · NOHelsinki University Hospital · FIKarolinska Institutet · SENorwegian Institute of Public Health · NOKarolinska University Hospital · SELiverpool School of Tropical Medicine · GBWestern Norway University of Applied Sciences · NOCenter for Child and Adolescent Mental Health, Eastern and Southern Norway · NODiakonhjemmet Hospital · NOInstitute for Community Health · USKing's College London · GBLinköping University Hospital · SENorwegian University of Science and Technology · NOStockholm University · SEUniversity of Helsinki · FIUniversity of Liverpool · GBVID Specialized University · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 'Oslo Chronic Fatigue Consortium' consists of researchers and clinicians who question the current narrative that chronic fatigue syndromes, including post-covid conditions, are incurable diseases. Instead, we propose an alternative view, based on research, which offers more hope to patients. Whilst we regard the symptoms of these conditions as real, we propose that they are more likely to reflect the brain's response to a range of biological, psychological, and social factors, rather than a specific disease process. Possible causes include persistent activation of the neurobiological stress response, accompanied by associated changes in immunological, hormonal, cognitive and behavioural domains. We further propose that the symptoms are more likely to persist if they are perceived as threatening, and all activities that are perceived to worsen them are avoided. We also question the idea that the best way to cope with the illness is by prolonged rest, social isolation, and sensory deprivation.Instead, we propose that recovery is often possible if patients are helped to adopt a less threatening understanding of their symptoms and are supported in a gradual return to normal activities. Finally, we call for a much more open and constructive dialogue about these conditions. This dialogue should include a wider range of views, including those of patients who have recovered from them.

Indexed as

Fatigue Syndrome, ChronicHumansChronic fatigue syndromeChronic illness narrativeLong CovidMultidimensional explanationsMyalgic encephalomyelitisPatient-centered careRehabilitation strategies

Identifiers

PMID37740918
PMCPMC11001335
OpenAlexW4386986559

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.