Evidence map›Paper›PMID 37740838›Full record

SynthesisLa Radiologia medica2024

Artificial intelligence applied to image-guided radiation therapy (IGRT): a systematic review by the Young Group of the Italian Association of Radiotherapy and Clinical Oncology (yAIRO).

Luca Boldrini, Andrea D'Aviero, Francesca De Felice, Isacco Desideri, Roberta Grassi, Carlo Greco, Giuseppe Carlo Iorio, Valerio Nardone, Antonio Piras, Viola Salvestrini

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in La Radiologia medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Systematic review of artificial intelligence in brachytherapy.Journal of contemporary brachytherapy · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. [Methods for enhancing image quality of soft tissue regions in synthetic CT based on cone-beam CT].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Luca BoldriniUOC Radioterapia Oncologica, Fondazione Policlinico Universitario IRCCS "A. Gemelli", Rome, Italy.
Andrea D'AvieroRadiation Oncology, Mater Olbia Hospital, Olbia, Sassari, Italy.
Francesca De FeliceRadiation Oncology, Department of Radiological, Policlinico Umberto I, Rome, Italy.
Isacco DesideriRadiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Roberta GrassiDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Carlo GrecoDepartment of Radiation Oncology, Università Campus Bio-Medico di Roma, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Giuseppe Carlo IorioDepartment of Oncology, Radiation Oncology, University of Turin, Turin, Italy.
Valerio NardoneDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Antonio PirasUO Radioterapia Oncologica, Villa Santa Teresa, Bagheria, Palermo, Italy. antoniopiras88@gmail.com.ORCID http://orcid.org/0000-0003-2361-9327
Viola SalvestriniRadiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Azienda Ospedaliero-Universitaria Careggi · ITUniversity of Campania "Luigi Vanvitelli" · ITOspedale Vincenzo Cervello · ITPoliclinico Umberto I · ITUniversità Campus Bio-Medico · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe advent of image-guided radiation therapy (IGRT) has recently changed the workflow of radiation treatments by ensuring highly collimated treatments. Artificial intelligence (AI) and radiomics are tools that have shown promising results for diagnosis, treatment optimization and outcome prediction. This review aims to assess the impact of AI and radiomics on modern IGRT modalities in RT.

methodsA PubMed/MEDLINE and Embase systematic review was conducted to investigate the impact of radiomics and AI to modern IGRT modalities. The search strategy was "Radiomics" AND "Cone Beam Computed Tomography"; "Radiomics" AND "Magnetic Resonance guided Radiotherapy"; "Radiomics" AND "on board Magnetic Resonance Radiotherapy"; "Artificial Intelligence" AND "Cone Beam Computed Tomography"; "Artificial Intelligence" AND "Magnetic Resonance guided Radiotherapy"; "Artificial Intelligence" AND "on board Magnetic Resonance Radiotherapy" and only original articles up to 01.11.2022 were considered.

resultsA total of 402 studies were obtained using the previously mentioned search strategy on PubMed and Embase. The analysis was performed on a total of 84 papers obtained following the complete selection process. Radiomics application to IGRT was analyzed in 23 papers, while a total 61 papers were focused on the impact of AI on IGRT techniques. DISCUSSION: AI and radiomics seem to significantly impact IGRT in all the phases of RT workflow, even if the evidence in the literature is based on retrospective data. Further studies are needed to confirm these tools' potential and provide a stronger correlation with clinical outcomes and gold-standard treatment strategies.

Indexed as

Radiation OncologyRadiotherapy, Image-GuidedArtificial IntelligenceHumansItalyRadiotherapy Planning, Computer-AssistedRetrospective StudiesArtificial intelligenceDeep learningImage-guided radiation therapyMachine learningRadiomics

Identifiers

PMID37740838
OpenAlexW4386982932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.