Evidence map›Paper›PMID 37740758›Full record

Trial reportWorld journal of surgery2023

Modified Enhanced Recovery After Surgery (ERAS) Protocol Versus Non-ERAS Protocol in Patients Undergoing Emergency Laparotomy for Acute Intestinal Obstruction: A Randomized Controlled Trial.

Ankit Aggarwal, Santosh Irrinki, Kailash C Kurdia, Siddhant Khare, Naveen Naik, Cherring Tandup, Ajay Savlania, Divya Dahiya, Lileswar Kaman, Yashwant Sakaray

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ankit AggarwalDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Santosh IrrinkiDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Kailash C KurdiaDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Siddhant KhareDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Naveen NaikDepartment of Anaesthesia, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Cherring TandupDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Ajay SavlaniaDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Divya DahiyaDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Lileswar KamanDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Yashwant SakarayDepartment of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India. sakaraypgi@gmail.com.ORCID 0000-0003-1095-7810
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced Recovery After Surgery (ERAS) is a multimodal approach with promising results in improving patient outcome. Only recently, is evidence emerging highlighting how similar principles of care can be applied to patients undergoing emergency abdominal surgery.

methodsA randomized controlled trial was conducted from November 2021 to April 2022 at PGIMER Chandigarh, which is a leading tertiary care hospital in northern India. 60 patients with acute intestinal obstruction requiring emergency laparotomy were randomized and assigned to ERAS or Non-ERAS group. ERAS protocol with some modifications was applied. Primary endpoints were post-operative hospital stay. Secondary end points were morbidity, 30-day readmission and mortality rate. Data analysis was done using SPSS 22.0. Independent t test or Mann-Whitney test and Chi-square or Fisher-exact test were used for analysis.

resultsA significant 3-day reduction in hospital stay was observed in ERAS compared to non-ERAS group (median (interquartile range) 5.50 (4.75-8.25) vs 8.0 (6.0-11.0) p = 0.003) with no difference in 30-day readmission rate, mortality rate and complication rate (according to Clavien-Dindo classification). ERAS group was associated with early recovery of gastrointestinal functions including time to first passage of flatus (p < 0.001), stools (p = 0.014), early ambulation (p < 0.001), time to first fluid diet (p < 0.001), solid diet (p = 0.001) and reduced nasogastric tube reinsertion rates (p = 0.01) despite its early removal.

conclusionERAS with some modifications can be applied in patients with intestinal obstruction. Thus, we can expedite post-operative recovery and early regain of gastrointestinal function with decreased hospital stay, comparable morbidity and mortality. Further studies are needed to assess ERAS role in emergency gastrointestinal surgeries. Trial registration Ctri.gov Identifier: CTRI/2022/04/042156.

Indexed as

Digestive System Surgical ProceduresEnhanced Recovery After SurgeryIntestinal ObstructionHumansLaparotomyLength of StayPostoperative Complications

Identifiers

PMID37740758
OpenAlexW4386987502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.