Evidence map›Paper›PMID 37740118›Full record

ArticleNature reviews. Genetics2023

Pioneer factors - key regulators of chromatin and gene expression.

Martha L Bulyk, Jacques Drouin, Melissa M Harrison, Jussi Taipale, Kenneth S Zaret

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Resolving Sub-Nuclear Architecture from Compartments to Functional Domains.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Decoding cnidarian cell type gene regulation.Nature ecology & evolution · 2026
    Article
  12. PervasivebioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. Cohesin Facilitates Nucleosome Invasion by Transcription Factors.bioRxiv : the preprint server for biology · 2025
    Article
  16. Circadian regulator REV-ERBα is a master regulator of tumor lineage plasticity and an effective therapeutic target.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Enhancer regulation in cancer: from epigenetics to mArchives of pharmacal research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martha L BulykDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. mlbulyk@genetics.med.harvard.edu.ORCID 0000-0002-3456-4555
Jacques DrouinLaboratoire de génétique moléculaire, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada. jacques.drouin@ircm.qc.ca.ORCID 0000-0001-8226-5691
Melissa M HarrisonDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA. mharrison3@wisc.edu.ORCID 0000-0002-8228-6836
Jussi TaipaleDepartment of Biochemistry, University of Cambridge, Cambridge, UK. ajt208@cam.ac.uk.ORCID 0000-0003-4204-0951
Kenneth S ZaretInstitute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. zaret@pennmedicine.upenn.edu.ORCID 0000-0001-8932-3145

Funding

TRANS-ACTING FACTORS CAUSING CELL-SPECIFIC GENE CONTROLR01GM036477 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ZARET, KENNETH · 1986 to 2023
$7.7M
Genomic reprogramming in the early embryoR35GM136298 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Melissa Harrison · 2020 to 2026
$2.8M
Influences of DNA sequence and histone features on transcription factor binding to nucleosomesR01HG012246 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI BULYK, MARTHA L · 2022 to 2025
$2.6M
Shared mechanisms regulate transcription-factor activity to control cell fate in neural stem cells and the embryoR01NS111647 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI HARRISON, MELISSA, LEE, CHENG-YU · 2019 to 2023
$1.7M
NHGRI NIH HHS R01 HG012246NIGMS NIH HHS R01 GM036477NIGMS NIH HHS R35 GM136298NINDS NIH HHS R01 NS111647
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChromatinNucleosomesGene ExpressionTranscription FactorsChromatinNucleosomesTranscription Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.