Evidence map›Paper›PMID 37739803›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2024

Ventilatory Effects of Fentanyl, Heroin, and

Takato Hiranita, Nicholas P Ho, Charles P France

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Reversal of morphine-induced respiratory depression with the µAmerican journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  5. Article
  6. Endogenous opioids and the development of the mammalian respiratory control network.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  7. Article
  8. Hypoxic effects of heroin and fentanyl and their basic physiological mechanisms.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  9. Article
  10. Comparison of theThe Journal of pharmacology and experimental therapeutics · 2024
    Article
  11. Article
  12. Goofball Polypharmacy.The Journal of pharmacology and experimental therapeutics · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Takato HiranitaDepartment of Pharmacology (T.H., N.P.H., C.P.F.), Department of Psychiatry (C.P.F.), and Addiction Research, Treatment & Training Center of Excellence (T.H., N.P.H., C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Nicholas P HoDepartment of Pharmacology (T.H., N.P.H., C.P.F.), Department of Psychiatry (C.P.F.), and Addiction Research, Treatment & Training Center of Excellence (T.H., N.P.H., C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Charles P FranceDepartment of Pharmacology (T.H., N.P.H., C.P.F.), Department of Psychiatry (C.P.F.), and Addiction Research, Treatment & Training Center of Excellence (T.H., N.P.H., C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas france@uthscsa.edu.
The University of Texas Health Science Center at Houston · USUniversity of Florida · US

Funding

DISCRIMINATIVE STIMULUS OF OPIOID WITHDRAWALR01DA005018 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 1988 to 2025
$8.8M
Methocinnamox (MCAM): A novel õ-opioid receptor antagonist for opioid use disordersUG3DA048387 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2019 to 2022
$2.9M
A novel opioid receptor antagonist for treating abuse and overdoseR01DA048417 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2019 to 2023
$2.6M
Gabapentinoid/opioid mixtures: abuse and toxicityR01DA058018 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Takato Hiranita · 2023 to 2026
$1.7M
NIDA NIH HHS R01 DA005018NIDA NIH HHS R01 DA048417NIDA NIH HHS R01 DA058018NIDA NIH HHS UG3 DA048387
6 · The paper itself

Abstract

The number of drug overdoses and deaths has increased significantly over the past decade and co-use of opioids and stimulants is associated with greater likelihood of overdose and decreased likelihood of accessing treatment, compared with use of opioids alone. Potential adverse effects of opioid/stimulant mixtures, particularly methamphetamine, are not well characterized. Two structurally different drugs with agonist properties at

Indexed as

Drug OverdoseMethamphetamineAnalgesics, OpioidAnimalsFentanylHeroinMaleNaloxoneRatsReceptors, OpioidAnalgesics, OpioidFentanylHeroinMethamphetamineNaloxoneReceptors, Opioid

Identifiers

PMID37739803
PMCPMC10801789
OpenAlexW4386948205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.