Evidence map›Paper›PMID 37739689›Full record

ArticleClinical nutrition ESPEN2023

Dairy product consumption and lung cancer risk: A prospective analysis.

Lan N Đoàn, Chenxiao Hu, Zhenzhen Zhang, Jackilen Shannon, Gerd Bobe, Yumie Takata

Open access · greenAbstract read
In one paragraph

Article in Clinical nutrition ESPEN, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lan N ĐoànCollege of Health, Health Promotion and Health Behavior Program, Oregon State University, Corvallis, OR, USA; Department of Population Health, Section for Health Equity, NYU Grossman School of Medicine, New York, NY, USA.
Chenxiao HuCollege of Sciences, Department of Statistics, Oregon State University, Corvallis, OR, USA.
Zhenzhen ZhangDivision of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Jackilen ShannonDivision of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Gerd BobeLinus Pauling Institute, Oregon State University, Corvallis, OR, USA.
Yumie TakataCollege of Health, Nutrition Program, Oregon State University, Corvallis, OR, USA. Electronic address: yumie.takata@oregonstate.edu.
Oregon State University · USOregon Health & Science University · US

Funding

Scaling Community-Clinical Linkage Models to Address Diabetes and Hypertension Disparities in the Southeastern U.S.U54MD000538 · NIMHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KWON, SIMONA, TRINH-SHEVRIN, CHAU · 2017 to 2022
$11.3M
NIMHD NIH HHS U54 MD000538
6 · The paper itself

Abstract

BACKGROUND &

aimCurrent evidence on prospective associations between dairy product, dairy fat and lactose intakes and lung cancer risk is limited and inconsistent. We conducted a prospective analysis of associations of lung cancer risk with dairy product intakes in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort.

methodsPre-diagnostic dairy product intake was assessed through a validated Diet History Questionnaire. All incident lung cancer cases were pathologically verified. Multivariable Cox regression was used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for associations of lung cancer risk with intakes of total, full-fat, low-fat dairy, fermented or non-fermented dairy products; milk fat content preference; and intakes of total and saturated fats and lactose from dairy products.

resultsAmong 101,709 adults (mean age of 65.5 years), a total of 1583 lung cancer cases were identified during 1,167,239 person-years of follow up. Mean total dairy product intake was 156 g/1000 kilocalories (kcal), including 20 g/1000 kcal from fermented dairy products. Total dairy intake was not associated with lung cancer risk (HR [95% CI] = 1.03 [0.89-1.18]) comparing the highest quartile with the lowest. Fermented dairy intake was inversely associated with lung cancer risk (0.85 [0.72-0.99]). In contrast, there were no statistically significant associations with low-fat, full-fat or non-fermented dairy product intakes. The preference of whole milk when consuming milk as beverage was associated with a higher risk of lung cancer than the preference of <0.5% fat milk (1.24 [1.03-1.49]). Total fat, saturated fat and lactose intakes from dairy products each were not associated with lung cancer risk.

conclusionsOur results suggest an inverse association of lung cancer risk with fermented dairy intake and a positive association with the whole milk preference in a US population. Future studies exploring underlying molecular mechanisms are warranted.

Indexed as

LactoseLung NeoplasmsAdultAgedAnimalsBeveragesHumansLungMaleMilkLactoseDairy foodsFood frequency questionnaireLactose intakeLung cancerObservational study

Identifiers

PMID37739689
PMCPMC10564330
OpenAlexW4383070325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.