ArticleJournal of advanced research2024
Identification and application of a candidate gene AhAftr1 for aflatoxin production resistance in peanut seed (Arachis hypogaea L.).
Article in Journal of advanced research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Ectopic Expression ofCurrent issues in molecular biology · 2026Article
- Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.).Plant biotechnology journal · 2026Article
- Genetic mapping and diagnostic marker development for a co-localization interval conferring resistance to both Aspergillus flavus infection and aflatoxin production in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genome-wide association studies unravel genomic regions and candidate genes associated with Aspergillus flavus resistance in peanut kernels.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Next-Generation Precision Breeding in Peanut (Insects · 2026Review
- Identification of AhFPA1 as the causal gene underlying qEFT13.1, a key QTL for early flowering in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome-wide identification of the peanut PITP gene family and functional verification of AhSFH8 in resistance to Aspergillus flavus infection.BMC plant biology · 2025Article
- CRISPR-Mediated Genome Editing in Peanuts: Unlocking Trait Improvement for a Sustainable Future.Plants (Basel, Switzerland) · 2025Review
- Aflatoxin Contamination in Agri-Food Systems: A Comprehensive Review of Toxicity, Food Security, Economic Impacts, and Sustainable Mitigation Across the Value Chain.Food science & nutrition · 2025Review
- Review
- Integration of BSA-seq and high-resolution mapping reveals genomic regions and candidate genes controlling seed oil accumulation in peanut (Arachis hypogaea L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Identification of candidate genes associated with resistance to aflatoxin production in peanut through genetic mapping and transcriptome analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeanut is susceptible to infection of Aspergillus fungi and conducive to aflatoxin contamination, hence developing aflatoxin-resistant variety is highly meaningful. Identifying functional genes or loci conferring aflatoxin resistance and molecular diagnostic marker are crucial for peanut breeding.
objectivesThis work aims to (1) identify candidate gene for aflatoxin production resistance, (2) reveal the related resistance mechanism, and (3) develop diagnostic marker for resistance breeding program.
methodsResistance to aflatoxin production in a recombined inbred line (RIL) population derived from a high-yielding variety Xuhua13 crossed with an aflatoxin-resistant genotype Zhonghua 6 was evaluated under artificial inoculation for three consecutive years. Both genetic linkage analysis and QTL-seq were conducted for QTL mapping. The candidate gene was further fine-mapped using a secondary segregation mapping population and validated by transgenic experiments. RNA-Seq analysis among resistant and susceptible RILs was used to reveal the resistance pathway for the candidate genes.
resultsThe major effect QTL qAFTRA07.1 for aflatoxin production resistance was mapped to a 1.98 Mbp interval. A gene, AhAftr1 (Arachis hypogaea Aflatoxin resistance 1), was detected structure variation (SV) in leucine rich repeat (LRR) domain of its production, and involved in disease resistance response through the effector-triggered immunity (ETI) pathway. Transgenic plants with overexpression of AhAftr1
conclusionOur findings would provide insights of aflatoxin production resistance mechanisms and laid meaningful foundation for further breeding programs.
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