Evidence map›Paper›PMID 37738972›Full record

ArticleCurrent biology : CB2023

Signaling protein abundance modulates the strength of the spindle assembly checkpoint.

Soubhagyalaxmi Jema, Chu Chen, Lauren Humphrey, Shriya Karmarkar, Frank Ferrari, Ajit P Joglekar

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Soubhagyalaxmi JemaDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Chu ChenDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Biophysics, University of Michigan, Ann Arbor, MI 48109, USA.
Lauren HumphreyDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Shriya KarmarkarDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Frank FerrariDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Ajit P JoglekarDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Biophysics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: ajitj@umich.edu.
University of Michigan · US

Funding

The systems biology of mitotic checkpoint signaling and its relevance to cancer cell biologyR35GM126983 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ajit Joglekar · 2018 to 2026
$5.1M
NIGMS NIH HHS R35 GM126983
6 · The paper itself

Abstract

During mitosis, unattached kinetochores in a dividing cell signal to the spindle assembly checkpoint (SAC) to delay anaphase onset and prevent chromosome missegregation.

Indexed as

Cell Cycle ProteinsM Phase Cell Cycle CheckpointsHumansKinetochoresMitosisSignal TransductionSpindle ApparatusCell Cycle Proteinscell cyclekinetochoremicroscopymitosissignalingspindle assembly checkpoint

Identifiers

PMID37738972
PMCPMC10615864
OpenAlexW4386926631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.