Evidence map›Paper›PMID 37738525›Full record

ArticleEuropean journal of neurology2024

Do monosymptomatic stroke patients with dizziness present a vestibular syndrome without nystagmus? An underestimated entity.

Florence Nikles, Hassen Kerkeni, Ewa Zamaro, Athanasia Korda, Franca Wagner, Thomas C Sauter, Roger Kalla, Miranda Morrison, Georgios Mantokoudis

Abstract read
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Acute truncal ataxia without nystagmus.European journal of neurology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Florence NiklesDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Hassen KerkeniDepartment of Neurology, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Ewa ZamaroDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Athanasia KordaDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Franca WagnerUniversity Institute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.ORCID 0000-0001-7502-4814
Thomas C SauterDepartment of Emergency Medicine, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Roger KallaDepartment of Neurology, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Miranda MorrisonDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Georgios MantokoudisDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.ORCID 0000-0003-2268-7811

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
6 · The paper itself

Abstract

background and purposeVestibular symptoms are common in emergency department (ED) patients and have various causes, including stroke. Accurate identification of stroke in patients with vestibular symptoms is crucial for timely management. We conducted a prospective cross-sectional study from 2015 to 2019 to determine stroke prevalence and associated symptoms in ED patients with vestibular symptoms, aiming to improve diagnosis and outcomes.

methodsAs part of the DETECT project, we screened 1647 ED patients with acute vestibular symptoms. Following a retrospective analysis of 961 head and neck magnetic resonance imaging (MRI) scans, we included 122 confirmed stroke cases and assessed them for vestibular signs and symptoms.

resultsStroke prevalence in dizzy patients was 13% (122/961 MRI scans). Most patients (95%) presented with acute vestibular symptoms with or without nystagmus, whereas 5% had episodic vestibular syndrome (EVS). Nystagmus was present in 50% of stroke patients. Eighty percent had a purely posterior circulation stroke, and nystagmus was absent in 46% of these patients. Seven patients (6%) had lesions in both the anterior and posterior circulation. Vertigo was experienced by 52% regardless of territory.

conclusionsA stroke was identified in 13% of ED patients presenting with acute vestibular symptoms. In 5%, it was EVS. Most strokes were in the posterior circulation territory; vertigo occurred with similar frequency in anterior and posterior circulation stroke, and absence of nystagmus was common in both.

Indexed as

Nystagmus, PathologicStrokeVestibular DiseasesCross-Sectional StudiesDizzinessHumansProspective StudiesRetrospective StudiesVertigoanterior circulationnystagmusposterior circulationstrokevertigo

Identifiers

PMID37738525
PMCPMC11235630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.