Evidence map›Paper›PMID 37738336›Full record

ArticleScience advances2023

Genetically determined thymic function affects strength and duration of immune response in COVID patients with pneumonia.

Hélène M Roux, Amira Marouf, Jacques Dutrieux, Bénédicte Charmeteau-De Muylder, Suzanne Figueiredo-Morgado, Véronique Avettand-Fenoel, Pelagia Cuvelier, Cécile Naudin, Fatma Bouaziz, Guillaume Geri and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04716907 (Thymic Function in Patients With COVID-19), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04716907 completednot on this map

Thymic Function in Patients With COVID-19

TypeobservationalSponsorCMC Ambroise ParéRan2021 to 2022Enrolled85ConditionsCovid19ArmsSingle-Nucleotide Polymorphisms (SNP) within the TCRA/D region, Blood sample, CT Scan, Bronchial fibroscopy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Long-Term Cancer and Mortality After Thymectomy.European journal of neurology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Hélène M RouxUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.ORCID 0000-0003-3847-8053
Amira MaroufGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.ORCID 0000-0002-5707-7290
Jacques DutrieuxUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.ORCID 0000-0003-4416-6136
Bénédicte Charmeteau-De MuylderUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.
Suzanne Figueiredo-MorgadoUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.
Véronique Avettand-FenoelUniversité Paris Cité, Faculté de médecine, Institut Cochin-CNRS 8104/INSERM U1016 AP-HP, Service de Virologie, Hôpital Cochin, Paris, France.ORCID 0000-0002-7022-2990
Pelagia CuvelierGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.ORCID 0009-0007-3303-1128
Cécile NaudinGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.
Fatma BouazizGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.
Guillaume GeriGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.
Anne Couëdel-CourteilleUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.ORCID 0000-0002-0060-2509
Pierre SquaraGroupe Hospitalier privé Ambroise Paré-Hartmann, Département Recherche Innovation, 92200, Neuilly-Sur-Seine, France.
Stefano MarulloUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.ORCID 0000-0001-9604-9973
Rémi CheynierUniversité Paris Cité, CNRS, INSERM, Institut Cochin, F-75014 Paris, France.ORCID 0000-0003-1146-660X
Centre National de la Recherche Scientifique · FRClinique Hartmann · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic activation improves the outcome of COVID-19 patients with severe pneumonia. The

Indexed as

COVID-19PneumoniaGenotypeHumansSARS-CoV-2Thymus Gland

Identifiers

PMID37738336
PMCPMC10516486
OpenAlexW4386951758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.