Evidence map›Paper›PMID 37738205›Full record

ArticleJournal of the American Chemical Society2023

Revisiting Coley's Toxins: Immunogenic Cardiolipins from

Yern-Hyerk Shin, Sunghee Bang, Sung-Moo Park, Xiao Ma, Chelsi Cassilly, Daniel Graham, Ramnik Xavier, Jon Clardy

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Journal of the American Chemical Society · 2025
    Article
  3. Review
  4. Transforming bacterial pathogens into wonder tools in cancer immunotherapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  5. Unusual Phospholipids fromJournal of the American Chemical Society · 2025
    Article
  6. Review
  7. Role of Innate Immunity in Cancer.Advances in experimental medicine and biology · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. A Cardiolipin fromJournal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yern-Hyerk ShinDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Sunghee BangDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.ORCID 0000-0002-6764-7373
Sung-Moo ParkBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Xiao MaDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Chelsi CassillyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Daniel GrahamBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Ramnik XavierBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Jon ClardyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.ORCID 0000-0003-0213-8356
Harvard University · USBroad Institute · US

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
Identification and Characterization of Microbial Metabolites in ImmunityR01AI172147 · NIAID · BROAD INSTITUTE, INC. · PI Daniel Bartholomew Graham, Ramnik J Xavier · 2022 to 2026
$3.9M
Identification and characterization of gut microbial bioactive molecules that determine predisposition to autoimmune disease and atopyR01AT009708 · NCCIH · HARVARD MEDICAL SCHOOL · PI CLARDY, JON, XAVIER, RAMNIK J · 2017 to 2021
$3.3M
600 MHz NMR Spectrometer ConsoleS10OD028526 · OD · HARVARD MEDICAL SCHOOL · PI WAGNER, GERHARD · 2020 to 2020
$649k
NCCIH NIH HHS R01 AT009708NIAID NIH HHS R01 AI172147NIDDK NIH HHS P30 DK043351NIH HHS S10 OD028526
6 · The paper itself

Abstract

Coley's toxins, an early and enigmatic form of cancer (immuno)therapy, were based on preparations of

Indexed as

NeoplasmsStreptococcus pyogenesCardiolipinsHumansTumor Necrosis Factor-alphaCardiolipinsTumor Necrosis Factor-alpha

Identifiers

PMID37738205
PMCPMC10557101
OpenAlexW4386954336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.