Evidence map›Paper›PMID 37737978›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Characterization of Linear IgE-Binding Epitopes in Food Allergens.

Changqi Liu, Sahil Gupta, Jing Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Changqi LiuSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA. changqi.liu@sdsu.edu.
Sahil GuptaGeneral Mills, Inc., Minneapolis, MN, USA.
Jing ZhaoSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An IgE epitope is a part of an allergen that is capable of binding to IgE antibodies and eliciting an immune response. Identifying and characterizing human-allergy-relevant epitopes are important for diagnosis and prognosis of food allergy and development of immunotherapy treatments. This chapter describes the protocol for manual synthesis of overlapping peptides on a cellulose membrane and subsequent dot blotting of the peptides with allergic patients' IgE to map the linear IgE-binding epitopes in food allergens.

Indexed as

Food HypersensitivityCelluloseEpitopesHumansImmunoglobulin EImmunotherapyCelluloseEpitopesImmunoglobulin EB cell epitopeEpitope mappingFood allergyLinear epitopeSPOT synthesis

Identifiers

PMID37737978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.