Evidence map›Paper›PMID 37737866›Full record

ArticleLangenbeck's archives of surgery2023

Lap. Nissen fundoplication leads to better respiratory symptom control than Toupet in the long term of 20 years.

Philipp Gehwolf, Teresa Agerer, Nadine Stacul, Katrin Kienzl-Wagner, Aline Schäfer, Valeria Berchtold, Fergül Cakar-Beck, Gasser Elisabeth, Heinz Wykypiel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Philipp GehwolfDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria. philipp.gehwolf@i-med.ac.at.
Teresa AgererDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Nadine StaculDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Katrin Kienzl-WagnerDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Aline SchäferDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Valeria BerchtoldDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Fergül Cakar-BeckDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Gasser ElisabethDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Heinz WykypielDepartment of Visceral, Transplant, and Thoracic Surgery (VTT), Center of Operative Medicine, Medical University of Innsbruck (MUI), 6020, Innsbruck, Austria.
Universität Innsbruck · ATInnsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHaving performed anti-reflux surgery for thirty years, it was important to reexamine our patients in the long term to enlarge the body of evidence concerning classical and extraesophageal symptoms that are differently controlled by Nissen or Toupet fundoplication.

objectivesWe report a cohort of 155 GERD patients who underwent fundoplication within a tailored approach between 1994 and 2000. Changes in the perioperative functional outcome, GERD symptoms, and quality of life are being analyzed 10 and 20 years after the operation.

resultsThe operation resulted in a superior quality of life compared to a patient cohort treated with PPI therapy. We found that both surgical methods (laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication) cure classical symptoms equally (heartburn, regurgitation, and dysphagia). GERD patients receiving a Toupet fundoplication seem more likely to suffer from extraesophageal GERD symptoms 10 and 20 years after surgery than patients with a Nissen fundoplication. On the other hand, some patients with Nissen fundoplication report dysphagia even 10 and 20 years after surgery.

conclusionBoth the laparoscopic Nissen and Toupet fundoplications provide excellent symptom control in the long term. Moreover, the Nissen fundoplication seems to be superior in controlling extraesophageal reflux symptoms, but at the expense of dysphagia. In summary, tailoring the operation based on symptoms seems advantageous.

Indexed as

Deglutition DisordersGastroesophageal RefluxLaparoscopyFundoplicationHumansQuality of LifeDeglutition disordersFundoplicationGastroesophageal refluxHeartburnHumansLaparoscopyQuality of life

Identifiers

PMID37737866
PMCPMC10517034
OpenAlexW4386945152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.