Evidence map›Paper›PMID 37737640›Full record

ArticleMicrobiology spectrum2023

Monocentric observational cohort study to investigate the transmission of third-generation cephalosporin-resistant Enterobacterales in a neonatal intensive care unit in Heidelberg, Germany.

Dennis Nurjadi, Vanessa M Eichel, Johannes Pöschl, Christian Gille, Simon Kranig, Klaus Heeg, Sébastien Boutin

Abstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dennis NurjadiDepartment of Infectious Diseases and Microbiology, University of Lübeck , Lübeck, Germany.ORCID 0000-0002-1278-5939
Vanessa M EichelDepartment of Medical Microbiology and Hygiene, Heidelberg University Hospital , Heidelberg, Germany.
Johannes PöschlDepartment of Neonatology, Heidelberg University Hospital, Heidelberg University Children's Hospital , Heidelberg, Germany.
Christian GilleDepartment of Neonatology, Heidelberg University Hospital, Heidelberg University Children's Hospital , Heidelberg, Germany.
Simon KranigDepartment of Neonatology, Heidelberg University Hospital, Heidelberg University Children's Hospital , Heidelberg, Germany.
Klaus HeegDepartment of Medical Microbiology and Hygiene, Heidelberg University Hospital , Heidelberg, Germany.
Sébastien BoutinDepartment of Infectious Diseases and Microbiology, University of Lübeck , Lübeck, Germany.ORCID 0000-0002-0499-2460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importancePreterm newborns are prone to infections. Therefore, infection prevention should be prioritized in this vulnerable patient group. However, outbreaks involving drug-resistant bacteria, such as third-generation resistant Enterobacterales, are often reported. Our study aims to investigate transmission and risk factors for acquiring third-generation cephalosporin-resistant Enterobacterales in a non-outbreak NICU setting. Our data indicated that premature birth and low birth weight are significant risk factors for colonization/infection with third-generation cephalosporin-resistant Enterobacterales. Furthermore, we could identify putative transmission clusters by whole-genome sequencing, highlighting the importance of preemptive measures to prevent infections in this patient collective.

Indexed as

antimicrobial resistancecephalosporin-resistant EnterobacteralesICUinfection prevention and controlneonatologytransmissionwhole-genome sequencing

Identifiers

PMID37737640
PMCPMC10581168

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.