Evidence map›Paper›PMID 37737443›Full record

ReviewApplied biochemistry and biotechnology2024

CRISPR-Based Gene Editing: a Modern Approach for Study and Treatment of Cancer.

Pratik Talukder, Sounak Chanda, Biswadeep Chaudhuri, Sonjoy Roy Choudhury, Debanjan Saha, Sudipta Dash, Abhineet Banerjee, Bhaskarjyaa Chatterjee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pratik TalukderDepartment of Biotechnology, University of Engineering and Management, Kolkata, West Bengal, 700156, India. pratik.talukder@uem.edu.in.ORCID http://orcid.org/0000-0003-2630-2392
Sounak ChandaDepartment of Biotechnology, University of Engineering and Management, Kolkata, West Bengal, 700156, India.
Biswadeep ChaudhuriDepartment of Biotechnology, University of Engineering and Management, Kolkata, West Bengal, 700156, India.
Sonjoy Roy ChoudhuryDepartment of Biotechnology, NIT, Rourkela, Odisha, 769001, India.
Debanjan SahaSchool of Biosciences and Technology, VIT, Vellore, Tamil Nadu, 632014, India.
Sudipta DashDepartment of Biotechnology, IIT, Kharagpur, West Bengal, 721302, India.
Abhineet BanerjeeDepartment of Biotechnology, NIT, Durgapur, West Bengal, 713209, India.
Bhaskarjyaa ChatterjeeDepartment of Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development and emergence of clustered regularly interspaced short palindromic repeats (CRISPR) as a genome-editing technology have created a plethora of opportunities in genetic engineering. The ability of sequence-specific addition or removal of DNA in an efficient and cost-effective manner has revolutionized modern research in the field of life science and healthcare. CRISPR is widely used as a genome engineering tool in clinical studies for observing gene expression and metabolic pathway regulations in detail. Even in the case of transgenic research and personalized gene manipulation studies, CRISPR-based technology is used extensively. To understand and even to correct the underlying genetic problem is of cancer, CRISPR-based technology can be used. Various kinds of work is going on throughout the world which are attempting to target different genes in order to discover novel and effective methodologies for the treatment of cancer. In this review, we provide a brief overview on the application of CRISPR gene editing technology in cancer treatment focusing on the key aspects of cancer screening, modelling and therapy techniques.

Indexed as

CRISPR-Cas SystemsGene EditingNeoplasmsAnimalsClustered Regularly Interspaced Short Palindromic RepeatsGenetic TherapyHumansCancerCRISPRGenetic engineeringGenome editingOncology

Identifiers

PMID37737443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.