Evidence map›Paper›PMID 37736990›Full record

ArticleTomography (Ann Arbor, Mich.)2023

Generating Synthetic Radiological Images with PySynthMRI: An Open-Source Cross-Platform Tool.

Luca Peretti, Graziella Donatelli, Matteo Cencini, Paolo Cecchi, Guido Buonincontri, Mirco Cosottini, Michela Tosetti, Mauro Costagli

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luca PerettiLaboratory of Medical Physics and Magnetic Resonance, IRCCS Stella Maris, 56128 Pisa, Italy.
Graziella DonatelliImago 7 Research Foundation, 56128 Pisa, Italy.ORCID 0000-0002-5325-0746
Matteo CenciniItalian National Institute of Nuclear Physics (INFN), Section of Pisa, 56127 Pisa, Italy.ORCID 0000-0001-7060-6305
Paolo CecchiImago 7 Research Foundation, 56128 Pisa, Italy.
Guido BuonincontriLaboratory of Medical Physics and Magnetic Resonance, IRCCS Stella Maris, 56128 Pisa, Italy.
Mirco CosottiniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Michela TosettiLaboratory of Medical Physics and Magnetic Resonance, IRCCS Stella Maris, 56128 Pisa, Italy.ORCID 0000-0002-2515-7560
Mauro CostagliLaboratory of Medical Physics and Magnetic Resonance, IRCCS Stella Maris, 56128 Pisa, Italy.ORCID 0000-0001-9073-1082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic MR Imaging allows for the reconstruction of different image contrasts from a single acquisition, reducing scan times. Commercial products that implement synthetic MRI are used in research. They rely on vendor-specific acquisitions and do not include the possibility of using custom multiparametric imaging techniques. We introduce PySynthMRI, an open-source tool with a user-friendly interface that uses a set of input images to generate synthetic images with diverse radiological contrasts by varying representative parameters of the desired target sequence, including the echo time, repetition time and inversion time(s). PySynthMRI is written in Python 3.6, and it can be executed under Linux, Windows, or MacOS as a python script or an executable. The tool is free and open source and is developed while taking into consideration the possibility of software customization by the end user. PySynthMRI generates synthetic images by calculating the pixelwise signal intensity as a function of a set of input images (e.g., T1 and T2 maps) and simulated scanner parameters chosen by the user via a graphical interface. The distribution provides a set of default synthetic contrasts, including T1w gradient echo, T2w spin echo, FLAIR and Double Inversion Recovery. The synthetic images can be exported in DICOM or NiFTI format. PySynthMRI allows for the fast synthetization of differently weighted MR images based on quantitative maps. Specialists can use the provided signal models to retrospectively generate contrasts and add custom ones. The modular architecture of the tool can be exploited to add new features without impacting the codebase.

Indexed as

RadiologyContrast MediaRetrospective StudiesSoftwareContrast Mediamagnetic resonance imagingsoftware toolsynthetic imaging

Identifiers

PMID37736990
PMCPMC10514862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.