Evidence map›Paper›PMID 37736983›Full record

ArticleTomography (Ann Arbor, Mich.)2023

Deep Learning-Based Versus Iterative Image Reconstruction for Unenhanced Brain CT: A Quantitative Comparison of Image Quality.

Andrea Cozzi, Maurizio Cè, Giuseppe De Padova, Dario Libri, Nazarena Caldarelli, Fabio Zucconi, Giancarlo Oliva, Michaela Cellina

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  7. AI for image quality and patient safety in CT and MRI.European radiology experimental · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Andrea CozziService of Radiology, Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Via Tesserete 46, 6900 Lugano, Switzerland.ORCID 0000-0003-4922-7065
Maurizio CèPostgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milano, Italy.ORCID 0000-0002-8906-5665
Giuseppe De PadovaPostgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milano, Italy.
Dario LibriPostgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milano, Italy.
Nazarena CaldarelliPostgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milano, Italy.
Fabio ZucconiDepartment of Radioprotection, Fatebenefratelli Hospital, ASST Fatebenefratelli Sacco, Milano, Piazza Principessa Clotilde 3, 20121 Milano, Italy.
Giancarlo OlivaRadiology Department, Fatebenefratelli Hospital, ASST Fatebenefratelli Sacco, Milano, Piazza Principessa Clotilde 3, 20121 Milano, Italy.
Michaela CellinaRadiology Department, Fatebenefratelli Hospital, ASST Fatebenefratelli Sacco, Milano, Piazza Principessa Clotilde 3, 20121 Milano, Italy.ORCID 0000-0002-7401-1971
University of Milan · ITFatebenefratelli Hospital · ITEnte Ospedaliero Cantonale · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This exploratory retrospective study aims to quantitatively compare the image quality of unenhanced brain computed tomography (CT) reconstructed with an iterative (AIDR-3D) and a deep learning-based (AiCE) reconstruction algorithm. After a preliminary phantom study, AIDR-3D and AiCE reconstructions (0.5 mm thickness) of 100 consecutive brain CTs acquired in the emergency setting on the same 320-detector row CT scanner were retrospectively analyzed, calculating image noise reduction attributable to the AiCE algorithm, artifact indexes in the posterior cranial fossa, and contrast-to-noise ratios (CNRs) at the cortical and thalamic levels. In the phantom study, the spatial resolution of the two datasets proved to be comparable; conversely, AIDR-3D reconstructions showed a broader noise pattern. In the human study, median image noise was lower with AiCE compared to AIDR-3D (4.7 vs. 5.3,

Indexed as

Deep LearningBrainHumansImage Processing, Computer-AssistedRetrospective StudiesTomography, X-Ray Computedbrain computed tomographydeep learning-based reconstruction algorithmsimage noiseimage qualityiterative reconstruction algorithms

Identifiers

PMID37736983
PMCPMC10514884
OpenAlexW4386322174

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.