Evidence map›Paper›PMID 37736927›Full record

ArticleClinics and practice2023

Rare Complication Post-Conization for Cervical Dysplasia: Rectovaginal Fistula.

Paolo Meloni, Sara Izzo, Claudia De Intinis, Terenzia Simari, Mariangela Motzo, Riccardo Picazzo, Rodolfo Brizio, Cristina Vignale, Marcello Molle, Luciano Izzo and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinics and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Paolo MeloniSC Ostetricia Ginecologia, Ospedale Imperia, ASL1 Imperiese, 18038 Sanremo, Italy.
Sara IzzoPlastic Surgery Unit, Multidisciplinary Department of Medical-Surgical and Dental Specialties, Università degli Studi della Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 80138 Naples, Italy.
Claudia De Intinis"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-5500-0268
Terenzia SimariAmbulatorio Specialistico Ginecologia Ostetricia, ASL1 Imperiese, 18038 Sanremo, Italy.
Mariangela MotzoSC Ostetricia Ginecologia, Ospedale Imperia, ASL1 Imperiese, 18038 Sanremo, Italy.
Riccardo PicazzoSC Radiologia, ASL1 Imperiese, 18038 Sanremo, Italy.
Rodolfo BrizioSC Anatomia Patologica, ASL1 Imperiese, 18038 Sanremo, Italy.
Cristina VignaleSC Anatomia Patologica, ASL1 Imperiese, 18038 Sanremo, Italy.
Marcello MollePlastic Surgery Unit, Multidisciplinary Department of Medical-Surgical and Dental Specialties, Università degli Studi della Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 80138 Naples, Italy.
Luciano Izzo"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-7852-032X
Paolo Izzo"Pietro Valdoni" Department of Surgery, Policlinico "Umberto I", "Sapienza" University of Rome, viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-4702-5171
Ospedale di Sanremo · ITPoliclinico Umberto I · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: High-grade cervical dysplasia is primarily caused by human papillomavirus (HPV) infection. Conservative surgery is the preferred treatment approach for this condition. The most commonly employed technique is the loop electrosurgical excision procedure (LEEP), which involves removing the affected portion of the cervix. Excisional treatments are often curative, and complications are typically rare and minor. (2) Methods: The loop electrosurgical excision procedure (LEEP) is the standard method used for conservative surgery in high-grade cervical dysplasia. It entails the excision of the specific area of the cervix where the abnormal cells are present. The procedure employs a wire loop carrying an electrical current to remove the affected tissue. (3) Results: Excisional treatments, such as LEEP, have shown to be effective in treating high-grade cervical dysplasia. They have a high success rate in eliminating abnormal cells and reducing the risk of cervical cancer. Complications associated with LEEP are infrequent and usually minor. Short-term complications may include bleeding, which can be managed easily. Long-term complications may involve cervical canal stenosis, which can impact fertility. (4) Conclusions: Conservative surgery, particularly the loop electrosurgical excision procedure (LEEP), is the preferred and effective treatment for high-grade cervical dysplasia caused by HPV infection. It offers a high cure rate with rare and minor complications. While short-term bleeding is a common occurrence, it is manageable. Long-term complications such as cervical canal stenosis may impact fertility. However, an extremely rare and possibly unique complication described in this case is the development of a vaginorectal fistula. This complication is likely due to indirect thermal injury resulting from compromised tissue. Further research is needed to better understand and prevent such complications.

Indexed as

cervical dysplasiacomplication post-conizationconizationrectovaginal fistula

Identifiers

PMID37736927
PMCPMC10514833
OpenAlexW4386134978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.