Evidence map›Paper›PMID 37736869›Full record

ArticleVeterinary research communications2024

Anticoccidial activity of Aloe Vera Leafs' aqueous extract and vaccination against Eimeria tenella: pathological study in broilers.

Shahenaz M H Hassan, Rasha Zayeda, H Elakany, Sohair Badr, A Abou-Rawash, Hoda Abd-Ellatieff

Open access · hybridAbstract read
In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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  6. Influence of HighAntibodies (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shahenaz M H HassanAlexandria Regional Laboratory, Animal Health Research Institute, Agriculture Research Center, Alexandria City, Egypt.
Rasha ZayedaAnimal Health Research Institute, Tanta Regional Laboratory, Tanta City, Egypt.
H ElakanyDepartment of Poultry and Fish diseases, Faculty of Veterinary Medicine, Damanhour University, Damanhour City, Egypt.
Sohair BadrPathology Department, Animal Health Research Institute Agriculture Research Center, Cairo City, Egypt.
A Abou-RawashDepartment of Pathology, Faculty of Veterinary Medicine, Damanhour University, Damanhour Cty, 25511, Egypt. rawashaa@yahoo.com.
Hoda Abd-EllatieffDepartment of Pathology, Faculty of Veterinary Medicine, Damanhour University, Damanhour Cty, 25511, Egypt.
Damanhour University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the efficacy of an anticoccidial vaccine and the anticoccidial activity of Aloe vera in broiler chickens infected with Eimeria tenella (E. tenella). A total of 225 healthy, sexless, one-day-old broiler chicks (avian48) from a commercial broiler company were randomized into nine experimental groups of 25 chicks. The groups were as follows: Group 1 (control, vaccinated, non-infected), Group 2 (vaccinated and infected with 5 × 104 sporulated oocysts), Group 3 (vaccinated, infected with 5 × 104 sporulated oocysts, and treated with Aloe vera), Group 4 (infected with 5 × 104 sporulated oocysts and treated with Aloe vera), Group 5 (positive control, infected with 5 × 104 sporulated oocysts), Group 6 (challenged with 5 × 104 sporulated oocysts and then treated with amprolium), Group 7 (treated with amprolium), Group 8 (blank control negative group), and Group 9 (treated with Aloe vera gel).Various parameters were evaluated, including clinical signs, growth performance, oocyst shedding, hematological and immunological parameters, and pathological lesion scoring. The results demonstrated that Aloe vera improved growth performance, reduced oocyst shedding, and decreased caecal lesion scores in E. Tenella-infected broiler chicks. The use of Aloe vera in combination with either amprolium or anticoccidial vaccines provided a potential solution to the issues of drug resistance and drug residues.In conclusion, this study provides valuable insights regarding the control of coccidiosis in broilers. Supplementing the chicken diet with Aloe vera had beneficial effects on the pathogenicity and infectivity of E. tenella, making it a cost-effective alternative as an herbal extract with no adverse side effects for coccidiosis control. These findings suggest that Aloe vera can be considered a potential candidate for inclusion in broiler diets for effective coccidiosis control.

Indexed as

AloeCoccidiosisEimeria tenellaPoultry DiseasesAmproliumAnimalsChickensOocystsPlant ExtractsVaccinationAmproliumPlant ExtractsAnticoccidial activity of Aloe VeraAnticoccidial activity of Aloe Vera and vaccinationAnticoccidial vaccinationPathology of E. tenella in broilers

Identifiers

PMID37736869
PMCPMC10811142
OpenAlexW4386944850

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.