Evidence map›Paper›PMID 37736816›Full record

ArticleCommunications biology2023

Intrinsically disordered regions in TRPV2 mediate protein-protein interactions.

Raghavendar R Sanganna Gari, Grigory Tagiltsev, Ruth A Pumroy, Yining Jiang, Martin Blackledge, Vera Y Moiseenkova-Bell, Simon Scheuring

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Thermosensing ability of TRPC5: current knowledge and unsettled questions.The journal of physiological sciences : JPS · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Raghavendar R Sanganna GariDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA.
Grigory TagiltsevDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0002-9312-2108
Ruth A PumroyDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-6200-6083
Yining JiangDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0002-7624-4488
Martin BlackledgeUniversité Grenoble Alpes, Centre National de la Recherche Scientifique (CNRS), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA), Institut de Biologie Structurale (IBS), 38000, Grenoble, France.ORCID http://orcid.org/0000-0003-0935-721X
Vera Y Moiseenkova-BellDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-0589-4053
Simon ScheuringDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA. sis2019@med.cornell.edu.ORCID http://orcid.org/0000-0003-3534-069X
Cornell University · USTranslational Therapeutics (United States) · USCentre National de la Recherche Scientifique · FR

Funding

Enabling physical stimuli in the study of structural dynamics: The sensory ion channelsDP1AT010874 · NCCIH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHEURING, SIMON · 2019 to 2023
$5.9M
Structure and Function of TRPV channelsR35GM144120 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Vera Moiseenkova-Bell · 2022 to 2026
$4.2M
Structural Insights into TRPV Channel GatingR01GM103899 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MOISEENKOVA-BELL, VERA · 2013 to 2021
$3.2M
High-speed atomic force microscopy with microsecond time resolution for the study of channels and transportersR01NS110790 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Simon Scheuring · 2019 to 2026
$2.4M
NCCIH NIH HHS DP1 AT010874NIGMS NIH HHS R01 GM103899NIGMS NIH HHS R35 GM144120NINDS NIH HHS R01 NS110790
6 · The paper itself

Abstract

Transient receptor potential (TRP) ion channels are gated by diverse intra- and extracellular stimuli leading to cation inflow (Na

Indexed as

Intrinsically Disordered ProteinsTRPV Cation ChannelsMicroscopy, Atomic ForceSingle Molecule ImagingIntrinsically Disordered ProteinsTRPV Cation Channels

Identifiers

PMID37736816
PMCPMC10516966
OpenAlexW4386944389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.