Evidence map›Paper›PMID 37736800›Full record

ArticleMolecular and cellular biochemistry2024

Inhibition of STIM1 alleviates high glucose-induced proliferation and fibrosis by inducing autophagy in mesangial cells.

Xixi Zeng, Anbang Sun, Weiyi Cheng, Xin Hou, Min Zhu, Yanhong Liao

Abstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The p53 target DRAM1 modulates calcium homeostasis and ER stress by promoting contact between lysosomes and the ER through STIM1.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Store-Operated CaContact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xixi ZengDepartment of Anatomy, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Anbang SunDepartment of Anatomy, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Weiyi ChengDepartment of Emergency Surgery, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Xin HouMedical College, Affiliated Hospital, Hebei University of Engineering, Handan, People's Republic of China.
Min ZhuDepartment of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China. mzhu@tjh.tjmu.edu.cn.
Yanhong LiaoDepartment of Anatomy, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China. yhliao1@hust.edu.cn.

Funding

Chen Xiao-Ping Foundation CXPJJH11900018-06Health Committee of Hubei Province of China WJ2019M146National Natural Science Foundation of China 31171087National Natural Science Foundation of China 81172786
6 · The paper itself

Abstract

Diabetic nephropathy (DN) is a renal microvascular complication caused by diabetes mellitus. One of the most typical characteristics of DN is glomerular mesangial cells (GMCs) proliferation. Stromal interaction molecule 1 (STIM1), a Ca

Indexed as

AutophagyCell ProliferationFibrosisGlucoseMesangial CellsStromal Interaction Molecule 1AnimalsCell LineDiabetes Mellitus, ExperimentalDiabetic NephropathiesMaleProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleySignal TransductionTOR Serine-Threonine KinasesGlucoseProto-Oncogene Proteins c-aktStim1 protein, ratStromal Interaction Molecule 1TOR Serine-Threonine KinasesAutophagyDiabetic nephropathyFibrosisProliferationSOCESTIM1

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.