Evidence map›Paper›PMID 37736535›Full record

ArticleVaccine: X2023

Production of recombinant lumpy skin disease virus A27L and L1R proteins for application in diagnostics and vaccine development.

Nomfundo Ntombela, Matome Matsiela, Sbahle Zuma, Suhavna Hiralal, Leeann Naicker, Nobalanda Mokoena, Thandeka Khoza

Abstract read
In one paragraph

Article in Vaccine: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nomfundo NtombelaDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Scottsville 3209, KwaZulu-Natal, South Africa.
Matome MatsielaDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Scottsville 3209, KwaZulu-Natal, South Africa.
Sbahle ZumaDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Scottsville 3209, KwaZulu-Natal, South Africa.
Suhavna HiralalDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Scottsville 3209, KwaZulu-Natal, South Africa.
Leeann NaickerOnderstepoort Biological Products (SOC. Ltd), 100, Old, Soutpan Road, Onderstepoort, 0110, Pretoria, South Africa.
Nobalanda MokoenaOnderstepoort Biological Products (SOC. Ltd), 100, Old, Soutpan Road, Onderstepoort, 0110, Pretoria, South Africa.
Thandeka KhozaDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Scottsville 3209, KwaZulu-Natal, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination using live attenuated vaccines (LAVs) is considered the most effective method for control of lumpy skin disease (LSD). However, this method is limited by safety concerns, with reports of adverse reactions following vaccination. This study evaluates A27L and L1R which are essential proteins for virus attachment and membrane fusion as recombinant sub-unit vaccines against LSD. These proteins were recombinantly expressed in

Indexed as

A27LL1RLumpy skin disease virusMontanide™ Gel 01 PRSubunit vaccines

Identifiers

PMID37736535
PMCPMC10509699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.