ArticleEuropean journal of obstetrics & gynecology and reproductive biology: X2023
Telephonic intervention to combat non-adherence to oral iron-folic acid supplementation in pregnancy: A randomized controlled trial.
Article in European journal of obstetrics & gynecology and reproductive biology: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Effectiveness of mHealth-Based Nutritional Interventions on Iron Status of Pregnant Women: Systematic Review of Randomized Controlled Trials.JMIR mHealth and uHealth · 2026Pooled it
- Effect of Nutrition Education During Pregnancy on Iron-Folic Acid Supplementation Compliance and Anemia in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.Nutrition reviews · 2025Pooled it
- Impact of digital health technology-based nutritional interventions on the nutritional status of hemodialysis patients: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Digital versus non-digital health interventions to improve iron supplementation in pregnant women: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Article
- Barriers and Facilitators of Compliance with Iron-Folic Acid Supplementation Among Pregnant Women in Southern Afghanistan: A Qualitative Study.Patient preference and adherence · 2026Article
- A scoping review of digital technologies in antenatal care: recent progress and applications of digital technologies.BMC pregnancy and childbirth · 2025Article
- The Jaga Diri digital intervention improved knowledge and adherence to weekly iron-folic acid supplementation among adolescent girls in Maluku Province, Indonesia.Frontiers in digital health · 2025Article
- Ironing Out the Details: How to Manage Anemia in Pregnancy in Women Living With CKD.Kidney international reports · 2024Article
- Mobile health (mHealth) interventions for health promotion during the perinatal period in India: a scoping review.Frontiers in global women's health · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Iron deficiency anemia is a public health problem globally attributing to high incidences of maternal and infant mortality and morbidity. Iron and folic acid supplementation (IFAS) is essential and provided free of cost by the public health sectors, however, a systematic review shows that the national-level adherence to oral Iron-Folic Acid Supplementation (IFAS) is less than half in pregnant women, and the significant obstacles to non-adherence are fear of side effects and forgetfulness. This trial was designed to mitigate the side effects and tackle forgetfulness with telephonic intervention. The objectives were to investigate the effectiveness of the telephonic intervention on oral IFAS adherence and hemoglobin and the reasons for non-adherence to oral IFAS, to find out the proportion of anemia in the study population, and to assess the effectiveness of the intervention on maternal and neonatal outcomes. Methods: Hospital-based open-label multi-centric parallel-group randomized controlled trial, used block randomization and allocated treatment in a 1:1 ratio recruited 286 anemic pregnant women between 14 and 24 weeks of gestation with hemoglobin level < 11 g/dl having smartphones at a secondary hospital and a tertiary hospital in Eastern India. The experimental group received telephonic intervention for one month via structured text reminders, WhatsApp audio messages, and phone calls. The standard course of treatment was given to the control group. Results: 286 women (n Conclusion: In addition to improving adherence to oral IFAS, telephonic intervention mitigates side effects and enhances hemoglobin in anemic pregnant women. The increase in adherence was threefold in the experimental group compared to a marginal rise in the control group. This study recommends the implementation of a telephonic intervention to promote adherence to oral IFAS among anemic pregnant women.
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