Evidence map›Paper›PMID 37735992›Full record

ReviewCNS neuroscience & therapeutics2024

NcRNAs: A synergistically antiapoptosis therapeutic tool in Alzheimer's disease.

Liangxian Li, Mingyue Jin, Jie Tan, Bo Xiao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liangxian LiLaboratory of Respiratory Disease, Affiliated Hospital of Guilin Medical University, Guilin, China.
Mingyue JinGuangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin, China.
Jie TanGuangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin, China.
Bo XiaoLaboratory of Respiratory Disease, Affiliated Hospital of Guilin Medical University, Guilin, China.ORCID 0009-0003-3512-8645

Funding

Open Project Program of Guangxi Key Laboratory of Brain and Cognitive Neuroscience (GKLBCN-20190103, GKLBCN-20190105-04, and GKLBCN-202106-02)Young and Middle aged Teachers' Basic Research Ability Improvement Project of Universities in Guangxi (2023KY0522 and 2023KY0541)
6 · The paper itself

Abstract

aimsThe aim of this review is to systematically summarize and analyze the noncoding RNAs (ncRNAs), especially microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), in the cell apoptosis among Alzheimer's disease (AD) in recent years to demonstrate their value in the diagnosis and treatment of AD.

methodsWe systematically summarized in vitro and in vivo studies focusing on the ncRNAs in the regulation of cell apoptosis among AD in PubMed, ScienceDirect, and Google Scholar.

resultsWe discover three patterns of ncRNAs (including 'miRNA-mRNA', 'lncRNA-miRNA-mRNA', and 'circRNA-miRNA-mRNA') form the ncRNA-based regulatory networks in regulating cell apoptosis in AD.

conclusionsThis review provides a future diagnosis and treatment strategy for AD patients based on ncRNAs.

Indexed as

Alzheimer DiseaseMicroRNAsRNA, Long NoncodingHumansRNA, CircularRNA, MessengerRNA, UntranslatedMicroRNAsRNA, CircularRNA, Long NoncodingRNA, MessengerRNA, UntranslatedADcell apoptosisNcRNAsregulatory network

Identifiers

PMID37735992
PMCPMC11017435

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.