Evidence map›Paper›PMID 37735882›Full record

ReviewGenesis (New York, N.Y. : 2000)2024

"Beyond transcription: How post-transcriptional mechanisms drive neural crest EMT".

Mariann Guzman-Espinoza, Minyoung Kim, Cindy Ow, Erica J Hutchins

Open access · hybridAbstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mariann Guzman-EspinozaDepartment of Cell and Tissue Biology, University of California San Francisco, San Francisco, California, USA.ORCID 0009-0003-5164-5941
Minyoung KimDepartment of Cell and Tissue Biology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-9502-1626
Cindy OwDevelopmental and Stem Cell Biology Graduate Program, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-8081-4682
Erica J HutchinsDepartment of Cell and Tissue Biology, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-4316-0333
University of California, San Francisco · US

Funding

UCSF INTEGRATED DDS-PHD TRAINING PROGRAMT32DE007306 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Yukiko Nakano · 1996 to 2026
$15.4M
Mechanisms of RNA turnover during the epithelial-mesenchymal transitionR35GM150763 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erica Hutchins · 2023 to 2026
$1.6M
Characterization of the roles and regulation of Draxin in cranial neural crestR00DE028592 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUTCHINS, ERICA · 2022 to 2024
$1.1M
NIDCR NIH HHS R00 DE028592NIDCR NIH HHS T32 DE007306NIGMS NIH HHS R35 GM150763
6 · The paper itself

Abstract

The neural crest is a stem cell population that originates from the ectoderm during the initial steps of nervous system development. Neural crest cells delaminate from the neuroepithelium by undergoing a spatiotemporally regulated epithelial-mesenchymal transition (EMT) that proceeds in a coordinated wave head-to-tail to exit from the neural tube. While much is known about the transcriptional programs and membrane changes that promote EMT, there are additional levels of gene expression control that neural crest cells exert at the level of RNA to control EMT and migration. Yet, the role of post-transcriptional regulation, and how it drives and contributes to neural crest EMT, is not well understood. In this mini-review, we explore recent advances in our understanding of the role of post-transcriptional regulation during neural crest EMT.

Indexed as

Epithelial-Mesenchymal TransitionNeural CrestCell MovementEctodermGene Expression Regulation, DevelopmentalNeural Tubecell migrationepithelial‐mesenchymal transitionneural crestpost‐transcriptional regulation

Identifiers

PMID37735882
PMCPMC10954587
OpenAlexW4386944462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.