Evidence map›Paper›PMID 37735699›Full record

ArticleEuropean journal of medical research2023

Postoperative ratio of C-reactive protein to albumin is an independent prognostic factor for gastric cancer.

Chenxi Li, Xuhui Yang, Hui Li, Yan Fu, Wenying Wang, Xin Jin, Lihua Bian, Liang Peng

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. A clinical-radiomic model based on best subset regression for prognostic prediction in natural killer/T-cell lymphoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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  8. The prealbumin-CD19BMC cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chenxi Li *Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Xuhui Yang *Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Hui Li *Department of Oncology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Yan Fu *Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Wenying WangSenior Department of Obstetrics & Gynecology, The Seventh Medical Center of PLA General Hospital, Beijing, China.
Xin JinSenior Department of Hepato-Pancreato-Biliary Surgery, The First Medical Center of PLA General Hospital, Beijing, China.
Lihua BianDepartment of Obstetrics and Gynecology, Hainan Hospital of PLA General Hospital, Sanya, China.
Liang PengSenior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China. pengliang_301@163.com.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe role of postoperative of the ratio of c-reactive protein to albumin (CRP/Alb ratio) in the prognosis of gastric cancer is rarely evaluated. Our purpose was to investigate the correlation of the postoperative CRP/Alb ratio and long-term prognosis of gastric cancer.

methodsWe enrolled 430 patients who suffered from radical gastrectomy. The commonly used inflammatory indices, clinical-pathological characteristics and oncologic outcomes were recorded. The median was used to the cut-off value for preoperative and postoperative CRP/Alb ratio, respectively. Kaplan-Meier analysis and Cox proportional hazards regression model were performed to determine its prognostic significance.

resultsIn univariate analysis, there were significant differences were observed in overall survival (OS) according to perioperative CRP/Alb ratio, c-reactive protein (CRP), serum albumin (Alb), respectively. According to the multivariate analysis, higher postoperative CRP/Alb ratio (HR 2.03, 95% CI 1.55-2.66, P < 0.001), lower postoperative albumin (Alb), higher preoperative c-reactive protein (CRP) and higher postoperative CRP were indicated a shorter overall survival.

conclusionPostoperative inflammatory factors in patients with gastric cancer should be pay attention, especially postoperative CRP/Alb ratio may be an independent predictor of long-term prognosis of gastric cancer.

Indexed as

C-Reactive ProteinStomach NeoplasmsHumansKaplan-Meier EstimatePrognosisSerum AlbuminC-Reactive ProteinSerum AlbuminGastric cancerOverall survivalPostoperative CRP/Alb ratioPreoperative CRP/Alb ratioPrognosis

Identifiers

PMID37735699
PMCPMC10515040
OpenAlexW4386923296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.