Evidence map›Paper›PMID 37735611›Full record

ArticleScientific reports2023

Genetic diversity and ancestry of the Khmuic-speaking ethnic groups in Thailand: a genome-wide perspective.

Jatupol Kampuansai, Rattanasak Wongkomonched, Wibhu Kutanan, Metawee Srikummool, Tanapon Seetaraso, Suwapat Sathupak, Patcharawadee Thongkumkoon, Apiwat Sangphukieo

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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jatupol KampuansaiDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand. Jatupol.K@cmu.ac.th.
Rattanasak WongkomonchedDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Wibhu KutananDepartment of Biology, Faculty of Science, Naresuan University, Phitsanulok, Thailand.
Metawee SrikummoolDepartment of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.
Tanapon SeetarasoDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Suwapat SathupakDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Patcharawadee ThongkumkoonCenter of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Apiwat SangphukieoCenter of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Khmuic-speaking populations are believed to be the descendants of one of the earliest groups to settle in Mainland Southeast Asia. In Thailand, there are two agricultural Khmuic-speaking ethnic groups, the Khamu and Lua (Htin). These peoples primarily reside in scattered locations along the mountainous Thailand-Laos border in Nan province. In this study, we conducted genome-wide SNP analysis on 81 individuals from three Khamu and two Lua villages in northern Thailand. Our findings revealed that both the Khamu and Lua groups possess genetic structures that are distinct from other ethnicities in Southeast Asia, indicating a unique history of migration and settlement. Within the Khmuic group, the Khamu populations living in different locations exhibited similar genetic structures and displayed genetic affinities only with some hill-tribes and Tai-Kadai (Kra-Dai)-speaking groups in Thailand, suggesting potential intermixing or cultural exchange. Furthermore, the Lua people displayed a distinctive population structure, which could be attributed to the founder effect and endogamous marriage practices. Additionally, we discovered a relationship between the Khmuic-speaking populations in Thailand and a Neolithic ancient sample obtained from the Tham Pha Ling archaeological site in Laos. This study provides new insight into genetic substructure within the Khmuic-speaking people and their potential relationship to the indigenous inhabitants of Mainland Southeast Asia.

Indexed as

AgricultureEthnicityArchaeologyGenetic VariationHumansThailand

Identifiers

PMID37735611
PMCPMC10514191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.