Evidence map›Paper›PMID 37735604›Full record

ArticleScientific reports2023

Virucidal activity of three standard chemical disinfectants against Ebola virus suspended in tripartite soil and whole blood.

Hulda R Jonsdottir, Daniel Zysset, Nicole Lenz, Denise Siegrist, Yelena Ruedin, Sarah Ryter, Roland Züst, Yannick Geissmann, Rahel Ackermann-Gäumann, Olivier B Engler and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hulda R Jonsdottir *Spiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland. hulda-run.jonsdottir@babs.admin.ch.
Daniel Zysset *Spiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland. daniel.zysset@babs.admin.ch.
Nicole Lenz *Spiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Denise SiegristSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Yelena RuedinSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Sarah RyterSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Roland ZüstSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Yannick GeissmannSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Rahel Ackermann-GäumannSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Olivier B EnglerSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
Benjamin WeberSpiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper disinfection and inactivation of highly pathogenic viruses is an essential component of public health and prevention. Depending on environment, surfaces, and type of contaminant, various methods of disinfection must be both efficient and available. To test both established and novel chemical disinfectants against risk group 4 viruses in our maximum containment facility, we developed a standardized protocol and assessed the chemical inactivation of the two Ebola virus variants Mayinga and Makona suspended in two different biological soil loads. Standard chemical disinfectants ethanol and sodium hypochlorite completely inactivate both Ebola variants after 30 s in suspension at 70% and 0.5% v/v, respectively, concentrations recommended for disinfection by the World Health Organization. Additionally, peracetic acid is also inactivating at 0.2% v/v under the same conditions. Continued vigilance and optimization of current disinfection protocols is extremely important due to the continuous presence of Ebola virus on the African continent and increased zoonotic spillover of novel viral pathogens. Furthermore, to facilitate general pandemic preparedness, the establishment and sharing of standardized protocols is very important as it allows for rapid testing and evaluation of novel pathogens and chemical disinfectants.

Indexed as

DisinfectantsEbolavirusHemorrhagic Fever, EbolaDisinfectionHumansSoilDisinfectantsSoil

Identifiers

PMID37735604
PMCPMC10514052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.