ArticleScientific reports2023
HU-based material conversion for BNCT accurate dose estimation.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Development of a scientific version TPS workflow for BNCT dosimetry based on DICOM and Monte Carlo engine.Physical and engineering sciences in medicine · 2026Article
- Development and evaluation of surface-guided patient position system for boron neutron capture therapy.Scientific reports · 2026Article
- Hypo-segmentation ofEJNMMI research · 2025Article
- Recurrent meningioma treated with boron neutron capture therapy: a feasibility study with dosimetric and clinical correlates.Journal of neuro-oncology · 2025Article
- MRI andScientific reports · 2025Article
- Automated robotic-assisted patient positioning method and dosimetric impact analysis for boron neutron capture therapy.Scientific reports · 2024Article
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Authors and funding
4 authors.
Funding
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Abstract
NeuMANTA is a new generation boron neutron capture therapy (BNCT)-specific treatment planning system developed by the Neuboron Medical Group and upgraded to an important feature, a Hounsfield unit (HU)-based material conversion algorithm. The range of HU values was refined to 96 specific groups and established corresponding to tissue information. The elemental compositions and mass densities have an important effect on the calculated dose distribution. The region of interest defined in the treatment plan can be converted into multiple material compositions based on HU values or assigned specified single material composition in NeuMANTA. Different material compositions may cause normal tissue maximum dose rates to differ by more than 10% in biologically equivalent doses and to differ by up to 6% in physically absorbed doses. Although the tumor has a lower proportion of BNCT background dose, the material composition difference may affect the minimum dose of biologically equivalent dose and physically absorbed dose by more than 3%. In addition, the difference in material composition could lead to a change in neutron moderation as well as scattering. Therefore, the material composition has a significant impact on the assessment of normal tissue side effects and tumor control probability. It is essential for accurate dose estimation in BNCT.
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