Evidence map›Paper›PMID 37735299›Full record

ArticleFood and environmental virology2023

Wastewater-based Epidemiology and SARS-CoV-2: Variant Trends in the Apulia Region (Southern Italy) and Effect of Some Environmental Parameters.

Francesco Triggiano, Osvalda De Giglio, Francesca Apollonio, Silvia Brigida, Fabrizio Fasano, Pamela Mancini, Giusy Bonanno Ferraro, Carolina Veneri, Giuseppina La Rosa, Elisabetta Suffredini and 6 more

Abstract readComment
In one paragraph

Article in Food and environmental virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Wastewater Surveillance of SARS-CoV-2 in Zambia: An Early Warning Tool.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Francesco Triggiano *Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, Bari, 70124, Italy.
Osvalda De Giglio *Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, Bari, 70124, Italy. osvalda.degiglio@uniba.it.
Francesca Apollonio *Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, Bari, 70124, Italy.
Silvia BrigidaDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Campus Ecotekne, Monteroni di Lecce, Lecce, 73047, Italy.
Fabrizio FasanoInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, Bari, 70124, Italy.
Pamela ManciniDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Giusy Bonanno FerraroDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Carolina VeneriDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Giuseppina La RosaDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Elisabetta SuffrediniDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Luca LucentiniDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, 00161, Italy.
Nicola UngaroAgency for the Environmental Prevention and Protection (ARPA Puglia), Corso Trieste 27, Bari, 70126, Italy.
Giuseppe Di VittorioDepartment of Health Promotion and Animal Welfare, Apulia Region, Bari, Italy.
Onofrio MongelliDepartment of Health Promotion and Animal Welfare, Apulia Region, Bari, Italy.
Nelhudoff AlbanoDepartment of Health Promotion and Animal Welfare, Apulia Region, Bari, Italy.
Maria Teresa MontagnaInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, Bari, 70124, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the COVID-19 pandemic, wastewater monitoring has been used to monitor the levels of SARS-CoV-2 RNA entering the sewerage system. In Italy, the Istituto Superiore di Sanità coordinated the SARI project (Sorveglianza Ambientale Reflue in Italia) to detect SARS-CoV-2 and its variants. In this study, the concentration of SARS-CoV-2 and its variants in raw wastewater against COVID-19 cases was evaluated together with the effect of temperature and precipitation on virus spread. We validated a predictive model, proposed by De Giglio et al., 2021, to establish the number of COVID-19 cases/100,000 inhabitants. A receiver operating characteristic curve model was applied to predict the number of COVID-19 cases and Poisson regression was applied to study the effect of temperature and rainfall on viral load. In Apulia, from October 2021 to December 2022, we analyzed 1041 samples, of which 985 (94.6%) tested positive for SARS-CoV-2. Median atmospheric temperature was inversely proportional to viral load in wastewater; no correlation was found with precipitation. The predictive model confirmed that at least 11 cases/100,000 inhabitants would occur in the 15 days following the detection of the virus in wastewater. Environmental surveillance of SARS-CoV-2 can be used to map the virus and its variants.

Indexed as

COVID-19SARS-CoV-2HumansItalyPandemicsRNA, ViralWastewaterWastewater-Based Epidemiological MonitoringRNA, ViralWastewaterCOVID-19SARS-CoV-2SewageWastewaterWastewater-based epidemiologyWastewater surveillance

Identifiers

PMID37735299
PMCPMC10654208

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.