ArticleThorax2023
Automatic analysis of bronchus-artery dimensions to diagnose and monitor airways disease in cystic fibrosis.
Article in Thorax, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Impact of 2 years of treatment with elexacaftor/tezacaftor/ivacaftor on longitudinal changes in structural lung disease in people with cystic fibrosis: results from the RECOVER trial.Annals of the American Thoracic Society · 2026Trial
- Chest CT imaging toward personalized management of chronic obstructive pulmonary disease, asthma, and bronchiectasis: pulmonologist perspectives.Japanese journal of radiology · 2026Review
- Stand-alone graph-based lung airway labeling with quantitative validations.Medical physics · 2026Article
- AI-driven CT quantification of mucus plugs to evaluate the effect of inhaled hypertonic saline in children aged 3-6 years with cystic fibrosis: a randomised controlled trial.The European respiratory journal · 2026Article
- Small Pulmonary Artery and Vein Volumes Independently Predict Oxygen Desaturation in Smokers.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- A novel quantitative method for CT assessment of bronchiectasis using AI-based airway segmentation and upper limits of normal airway caliber.Respiratory research · 2026Article
- Pseudomonas aeruginosa phenotypes associated with radiological severity in non-cystic fibrosis bronchiectasis.BMC pulmonary medicine · 2026Article
- Clinical benefit without sweat chloride response after ETI therapy in an adult with cystic fibrosis bearing the L467F;F508del complexFrontiers in medicine · 2026Article
- The impact of dornase alfa on imaging features of bronchiectasis.Research square · 2025Article
- Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation.Cell host & microbe · 2025Article
- Normative values for lung, bronchial sizes, and bronchus-artery ratios in chest CT scans: from infancy into young adulthood.European radiology · 2025Article
- Automated computed tomographic analysis of bronchial thickness and mucus plugs in bronchiectasis with asthma.ERJ open research · 2025Article
- Effect of inspiratory lung volume on bronchial and arterial dimensions and ratios on chest computed tomography in patients with chronic obstructive pulmonary disease.European radiology · 2025Article
- Evolution of Lung Disease Studied by Computed Tomography in Adults with Cystic Fibrosis Treated with Elexacaftor/Tezacaftor/Ivacaftor.Journal of imaging · 2025Article
- Introduction of Ivacaftor/Lumacaftor in Children With Cystic Fibrosis Homozygous for F508del in the Netherlands: A Nationwide Real-Life Study.Pediatric pulmonology · 2025Article
- Automated method of bronchus and artery dimension measurement in an adult bronchiectasis population.ERJ open research · 2024Article
- Higher small pulmonary artery and vein volume on computed tomography is associated with mortality in current and former smokers.EBioMedicine · 2024Article
- Evolving and Novel Applications of Artificial Intelligence in Thoracic Imaging.Diagnostics (Basel, Switzerland) · 2024Review
- Reply to Dournes and Benlala: Hierarchical Computed Tomography Scoring Systems Cannot Discriminate Between Reversible Bronchiectasis and Mucus Plugs.American journal of respiratory and critical care medicine · 2024Article
- Children with severe asthma have substantial structural airway changes on computed tomography.ERJ open research · 2024Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystic fibrosis (CF) lung disease is characterised by progressive airway wall thickening and widening. We aimed to validate an artificial intelligence-based algorithm to assess dimensions of all visible bronchus-artery (BA) pairs on chest CT scans from patients with CF.
methodsThe algorithm fully automatically segments the bronchial tree; identifies bronchial generations; matches bronchi with the adjacent arteries; measures for each BA-pair bronchial outer diameter (B
resultsThe automatic and manual BA analysis showed no significant differences in quantifying bronchi. For the longitudinal datasets the automatic BA analysis detected 247 and 347 BA pairs/CT in the Copenhagen and ataluren dataset, respectively. A significant increase of 0.02 of B
conclusionThe BA analysis can fully automatically analyse a large number of BA pairs on chest CTs to detect and monitor progression of bronchial wall thickening and bronchial widening in patients with CF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.